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AB9084 Anti-Polycystin-L Antibody

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AB9084
100 µL  
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      概述

      Replacement Information

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, ICC, IHCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB9084
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Polycystin-L Antibody
      References
      Product Information
      FormatSerum
      Control
      • POSITIVE CONTROL: adult mouse retina

        NEGATIVE CONTROL: adult mouse lung
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Polycystin-L Antibody is validated for use in WB, IC, IH for the detection of Polycystin-L.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesWestern blot: 1:1,000 using ECL. The antibody reacts with the 90 kDa Polycystin1-L1 protein. Suggested blocking buffer is 10% normal goat serum (or same host as your secondary antibody), 1% BSA in 0.1M PBS with 0.05% Tween 20. Suggested dilution buffer is 1% normal goat serum (or same host as your secondary antibody), 1% BSA in 0.1M PBS with 0.05% Tween 20. Preferred gel percentage is 4-12% gradient gel.

      Immunocytochemistry: 1:1,000

      Immunohistochemistry: 1:1,000 overnight at 2-8°C using a fluorescently labeled secondary antibody. Suggested fixative is 4% paraformaldehyde in 0.1M PBS (one hour). Suggested permeablization method is 0.05% Triton X-100 in dilution buffer. Suggested blocking buffer is 10% normal goat serum (or same host as your secondary antibody) and 1% BSA in 0.1M PBS. Suggested dilution buffer is 1% normal goat serum (or same host as your secondary antibody) and 1% BSA in 0.1M PBS.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the N-terminal of human Polycystin-L1.
      HostRabbit
      SpecificityPolycystin-L
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined.
      Gene Symbol
      • PKD2L1
      • Polycystic kidney disease-2 like 1 protein
      • Polycystin-2 homolog
      • PK2L1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q8TDX9 # May have a role in the heart and in the male reproductive system.
      SIZE: 2849 amino acids; 315435 Da
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
      TISSUE SPECIFICITY: Detected in testis and in fetal and adult heart.
      SIMILARITY: SwissProt: Q8TDX9 ## Belongs to the polycystin family. & Contains 1 GPS domain. & Contains 2 PKD domains. & Contains 1 PLAT domain. & Contains 1 REJ domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      AB9084 04053252337154

      Documentation

      Anti-Polycystin-L Antibody MSDS

      职位

      物料安全数据表 (MSDS) 

      Anti-Polycystin-L Antibody 分析证书

      标题批号
      RABBIT ANTI-POLYCYSTIN-L POLYCLONAL ANTIBODY - 2459032 2459032
      RABBIT ANTI-POLYCYSTIN-L - 3204874 3204874
      RABBIT ANTI-POLYCYSTIN-L - 3398590 3398590
      RABBIT ANTI-POLYCYSTIN-L - 3546490 3546490
      RABBIT ANTI-POLYCYSTIN-L - 3674969 3674969
      RABBIT ANTI-POLYCYSTIN-L - 3910193 3910193
      RABBIT ANTI-POLYCYSTIN-L - 4019801 4019801
      RABBIT ANTI-POLYCYSTIN-L - 4182481 4182481
      RABBIT ANTI-POLYCYSTIN-L - 4215034 4215034
      RABBIT ANTI-POLYCYSTIN-L -2539257 2539257

      参考

      参考概述公共医疗ID
      Morphology, distribution and phenotype of polycystin kidney disease 2-like 1-positive cerebrospinal fluid contacting neurons in the brainstem of adult mice.
      Orts-Del'Immagine, A; Kastner, A; Tillement, V; Tardivel, C; Trouslard, J; Wanaverbecq, N
      PloS one  9  e87748  2014

      显示摘要
      24504595 24504595
      Polycystin-2 expression and function in adult mouse lacrimal acinar cells.
      Kaja, S; Hilgenberg, JD; Rybalchenko, V; Medina-Ortiz, WE; Gregg, EV; Koulen, P
      Investigative ophthalmology & visual science  52  5605-11  2011

      显示摘要
      21508103 21508103

      数据表

      标题
      RABBIT ANTI-POLYCYSTIN-L POLYCLONAL ANTIBODY