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MABN476 Sigma-AldrichAnti-Paris/ZNF746 Antibody, clone N196/16

Anti-Paris/ZNF746 Antibody, clone N196/16 is a highly specific mouse monoclonal antibody & that targets Zinc Finger Protein & has been tested in western blotting.

Anti-Paris/ZNF746 Antibody, clone N196/16 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: ZNF746, PARIS UniProt Number: Q6NUN9

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概述

Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	WB	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABN476
Description	Anti-Paris/ZNF746 Antibody, clone N196/16
Alternate Names	Zinc finger protein 746 Parkin-interacting substrate PARIS
Background Information	Zinc finger protein 746 (ZNF746) is also called Parkin-interacting substrate (PARIS). ZNF746 is a repressor of transcription that binds to promoters and represses the transcription of PGC-1-alpha (PPARGC1A), making it important to the regulation of neuron death. ZNF746 may also contribute to neurodegeneration in Parkinson disease.

References

Product Information
Format	Purified
Control	HEK293 cell lysate
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-Paris/ZNF746 Antibody, clone N196/16 is a highly specific mouse monoclonal antibody & that targets Zinc Finger Protein & has been tested in western blotting.
Key Applications	Western Blotting
Application Notes	Western Blotting Analysis: 1 µg/mL of this antibody detected Paris/ZNF746 in 10 µg of RAW264.7 cell lysate. Immunohistochemistry Analysis: A representative lot detected Paris/ZNF746 in rat brain tissue (Prof. J. Trimmer, University of California, Davis.).

Biological Information
Immunogen	Recombinant protein corresponding to the N-terminus of human Paris/ZNF746.
Epitope	N-terminus
Clone	N196/16
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	This antibody recognizes the N-terminus of ZNF746. This antibody does not cross react with ZNF783 or ZNF398 (Prof. J. Trimmer, University of California, Davis.).
Isotype	IgG1κ
Species Reactivity	Human Mouse Rat
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001156946
Gene Symbol	ZNF746 PARIS
Purification Method	Protein G Purified
UniProt Number	Q6NUN9
Molecular Weight	~72 kDa observed. Uniprot describes 3 isoforms, two at 69 kDa and one at 49 kDa. This protein is ubiquitinated and has been observed at higher molecular weights (Shin, J. H., et al. (2011). Cell. 144(5):689-702.).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in HEK293 cell lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected Paris/ZNF746 in 10 µg of HEK293 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABN476	04053252912443

Documentation

Anti-Paris/ZNF746 Antibody, clone N196/16 MSDS

职位
物料安全数据表 (MSDS)

Anti-Paris/ZNF746 Antibody, clone N196/16 分析证书

标题	批号
Anti-Paris/ZNF746 clone N196/16 - 3251023	3251023
Anti-Paris/ZNF746 clone N196/16 - 3462123	3462123
Anti-Paris/ZNF746 clone N196/16 - 3521077	3521077
Anti-Paris/ZNF746 clone N196/16 - 3698723	3698723
Anti-Paris/ZNF746 clone N196/16 - 3831722	3831722
Anti-Paris/ZNF746 clone N196/16 - 3988531	3988531
Anti-Paris/ZNF746 clone N196/16 - 4138112	4138112
Anti-Paris/ZNF746 clone N196/16 - 4158362	4158362
Anti-Paris/ZNF746 clone N196/16 - Q2204790	Q2204790
Anti-Paris/ZNF746 clone N196/16 -2809944	2809944

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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