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MABS462 Sigma-AldrichAnti-PER2, clone 7H4.1 Antibody

Anti-PER2, clone 7H4.1 Antibody is an antibody against PER2 for use in Western Blotting and Immunohistochemistry (Paraffin).

Anti-PER2, clone 7H4.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

分析证书
技术信息

Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: PER2, KIAA0347 UniProt Number: O15055

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Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IH(P)	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABS462
Description	Anti-PER2, clone 7H4.1 Antibody
Alternate Names	PER2 Period circadian protein homolog 2 hPER2 Circadian clock protein PERIOD 2
Background Information	Period circadian protein homolog 2 (PER2), or Circadian clock protein PERIOD2, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. It is a negative element in the circadian transcriptional loop by Influencing clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. PER2 negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ300

Applications
Application	Anti-PER2, clone 7H4.1 Antibody is an antibody against PER2 for use in Western Blotting and Immunohistochemistry (Paraffin).
Key Applications	Western Blotting Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected PER2 in human pancreas and human kidney tissue.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to human PER2.
Clone	7H4.1
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_073728
Gene Symbol	PER2 KIAA0347
Purification Method	Protein G Purified
UniProt Number	O15055
Molecular Weight	~136 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in HepG2 nuclear extract. Western Blotting Analysis: 0.5 µg/mL of this antibody detected PER2 in 200 µg of HepG2 nuclear extract.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABS462	04055977136852

Documentation

Anti-PER2, clone 7H4.1 Antibody 分析证书

标题	批号
Anti-PER2, clone 7H4.1 - 4070052	4070052
Anti-PER2, clone 7H4.1 -Q2559135	Q2559135

技术信息

标题
White Paper: Further considerations of antibody validation and usage.

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产品目录编号

描述

AB5428P

Anti-Per2 Antibody

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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