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MABE78 Sigma-AldrichAnti-MiTF Antibody, clone 3D1.2

Anti-MiTF Antibody, clone 3D1.2 is an antibody against MiTF for use in Western Blotting & IHC.

Anti-MiTF Antibody, clone 3D1.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Signaling Research Sub-Category: Transcription Factors Gene Symbol: MITF, BHLHE32 UniProt Number: O75030

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB, IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABE78
Replaces	MAB3747
Description	Anti-MiTF Antibody, clone 3D1.2
Alternate Names	Microphthalmia-associated transcription factor Class E basic helix-loop-helix protein 32 bHLHe32
Background Information	Microphthalmia-associated transcription factor (MiTF) is a basic helix loop helix leucine zipper (b HLH ZIP) transcription factor implicated in pigmentation, and development of mast cells and bone. Mutations in MiTF cause auditory pigmentary syndromes in humans, such as Waardenburg syndrome type II and type IIa, and Tietz syndrome. There are two known isoforms of MiTF, differing by 66 amino acids at the N-terminus. Shorter forms are expressed in melanocytes and run as two bands at 52 kDa and 56 kDa, whereas the longer Mi form runs as a cluster of bands at 60-70 kDa in osteoclasts and in B16 melonoma cells (but not other melanoma cell lines), as well as mast cells and heart. MiTF plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

References

Product Information
Format	Purified
Control	Mouse brain tissue lysate
Presentation	Purified mouse monoclonal IgMκ in buffer containing 0.01M PBS, 0.1% Sodium Azide, pH 7.1.
Quality Level	MQ100

Applications
Application	Anti-MiTF Antibody, clone 3D1.2 is an antibody against MiTF for use in Western Blotting & IHC.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected MiTF in human melanoma tissue.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to human MiTF.
Clone	3D1.2
Host	Mouse
Isotype	IgMκ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_000239
Gene Symbol	MITF BHLHE32
UniProt Number	O75030
Molecular Weight	~52 kDa observed. Multiple isoforms between 46-56 kDa are known to exist.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blot in mouse brain tissue lysate. Western Blot Analysis: A 1:500 dilution of this antibody detected MiTF in 10 µg of mouse brain tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	200 µL

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABE78	04053252698842

Documentation

Anti-MiTF Antibody, clone 3D1.2 MSDS

职位
物料安全数据表 (MSDS)

Anti-MiTF Antibody, clone 3D1.2 分析证书

标题	批号
Anti-MiTF, clone 3D1.2 - 2562843	2562843
Anti-MiTF, clone 3D1.2 - 3270773	3270773
Anti-MiTF, clone 3D1.2 - 3734543	3734543
Anti-MiTF, clone 3D1.2 - Q2060583	Q2060583
Anti-MiTF, clone 3D1.2 -2650908	2650908
Anti-MiTF, clone 3D1.2 -2712568	2712568
Anti-MiTF, clone 3D1.2 -2750089	2750089
Anti-MiTF, clone 3D1.2 -2793645	2793645
Anti-MiTF, clone 3D1.2 Monoclonal Antibody	3050686
Anti-MiTF, clone 3D1.2 Monoclonal Antibody	3499348

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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