数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABS186 Sigma-AldrichAnti-LOX-1, clone 9E12.1

Anti-LOX-1 Antibody, clone 9E12.1 is an antibody against LOX-1 for use in Immunohistochemistry and Immunocytochemistry (Paraffin).

Anti-LOX-1, clone 9E12.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
小册子
技术信息

Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: OLR1, CLEC8A, LOX1 UniProt Number: P78380

View Products on Sigmaaldrich.com

Recommended Products

概述

Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IH(P)	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABS186
Description	Anti-LOX-1, clone 9E12.1
Alternate Names	LOX-1 Oxidized low-density lipoprotein receptor 1 Ox-LDL receptor 1 C-type lectin domain family 8 member A Lectin-like oxidized LDL receptor 1 Lectin-like oxLDL receptor 1 hLOX-1 Lectin-type oxidized LDL receptor 1 Oxidized low-density lipoprotein receptor 1, soluble form
Background Information	LOX1 is a plasma membrane receptor, that also has a free soluble receptor form, that is the receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. LOX1 is also the receptor for HSP70, and LOX1 acts as a leukocyte adhesion molecule on glycosylated proteins present on platelets, monocytes, bacteria, apoptotic cells in inflammatory responses.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-LOX-1 Antibody, clone 9E12.1 is an antibody against LOX-1 for use in Immunohistochemistry and Immunocytochemistry (Paraffin).
Key Applications	Western Blotting Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LOX-1 in human placenta tissue.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to human LOX-1.
Clone	9E12.1
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG2aκ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001166103
Gene Symbol	OLR1 CLEC8A LOX1
Purification Method	Protein G Purified
UniProt Number	P78380
Molecular Weight	~35 kDa observed. The calculated molecular weight of this protein is 31 kDa, but can be observed at ~33-37 kDa due to high glycosylation.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in KG-1 cell lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected LOX-1 in 200 µg of KG-1 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABS186	04055977135367

Documentation

Anti-LOX-1, clone 9E12.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-LOX-1, clone 9E12.1 分析证书

标题	批号
Anti-LOX-1, clone 9E12.1 - 3191404	3191404
Anti-LOX-1, clone 9E12.1 - 3532303	3532303
Anti-LOX-1, clone 9E12.1 - 3670610	3670610
Anti-LOX-1, clone 9E12.1 - 3923043	3923043
Anti-LOX-1, clone 9E12.1 - 4070063	4070063
Anti-LOX-1, clone 9E12.1 -2892459	2892459
Anti-LOX-1, clone 9E12.1 -Q2550834	Q2550834
Anti-LOX-1, clone 9E12.1 Monoclonal Antibody	3030539
Anti-LOX-1, clone 9E12.1 Monoclonal Antibody	2872172
Anti-LOX-1, clone 9E12.1 Monoclonal Antibody	3768033

小册子

标题
NPI Flyer- Epigenetics and Nuclear Function Feature
New Products - Antibodies, Small Molecule, Inhibitors

技术信息

标题
White Paper: Further considerations of antibody validation and usage.

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

此产品已添加到您的购物车。