数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

423500 Sigma-AldrichAnti-Klotho Rabbit pAb

This Anti-Klotho Rabbit pAb is validated for use in ELISA, Immunoblotting for the detection of Klotho.

Anti-Klotho Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: Anti-KL

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概述

Replacement Information

重要规格表

Species Reactivity	Host	Antibody Type
M	Rb	Polyclonal Antibody

价格及供货情况

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Description
Overview	Recognizes the ~100 kDa Klotho protein.
Catalogue Number	423500
Brand Family	Calbiochem®
Synonyms	Anti-KL

References
References	Kuro-o, M., et al. 1997. Nature 390, 45. Martin, G.M. and Mian, I.S. 1997. Nature 390, 18.

Product Information
Form	Liquid
Formulation	In PBS, 0.1% BSA, pH 7.5.
Preservative	None
Quality Level	MQ100

Applications
Key Applications	Enzyme-Linked Immunosorbent Assay Immunoblotting (Western Blotting)
Application Notes	ELISA (1:10,000-1:100,000) Immunoblotting (1-10 µg/ml, chemiluminescence)
Application Comments	Variables associated with assay conditions will dictate the optimal working dilution.

Biological Information
Immunogen	a synthetic peptide corresponding to a 17-amino acid sequence near the C-terminus of murine Klotho
Immunogen	Mouse
Host	Rabbit
Isotype	IgG
Species Reactivity	Mouse
Antibody Type	Polyclonal Antibody
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	-20°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
423500-50UGCN	04055977187304

Documentation

Anti-Klotho Rabbit pAb MSDS

职位
物料安全数据表 (MSDS)

Anti-Klotho Rabbit pAb 分析证书

标题	批号
423500	输入批号

参考

参考信息概述
Kuro-o, M., et al. 1997. Nature 390, 45. Martin, G.M. and Mian, I.S. 1997. Nature 390, 18.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	08-October-2009 RFH
Synonyms	Anti-KL
Application	ELISA (1:10,000-1:100,000) Immunoblotting (1-10 µg/ml, chemiluminescence)
Description	Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~100 kDa Klotho protein.
Background	Inactivation mutation of the recently discovered klotho gene in mice causes a syndrome resembling aging. Homozygous mutant klotho (kl/kl) mice exhibit premature aging phenotypes such as osteoporosis, age related skin changes, ectopic calcification, atrophy of genital organs and thymus, atherosclerosis, emphysema, ataxia, and short life span. The kl gene encodes a membrane protein whose extracellular domain carries homology to β-glucosidases. There also exists a splice variant of kl mRNA that encodes a putative secreted protein in both human and mouse. kl gene expression was observed to be tissue specific. Improvement of systemic aging phenotypes in kl/kl mice occurs even when the exogenous expression was limited to some organs, suggesting that KL associated aging is regulated through a humoral signaling pathway.
Host	Rabbit
Immunogen species	Mouse
Immunogen	a synthetic peptide corresponding to a 17-amino acid sequence near the C-terminus of murine Klotho
Isotype	IgG
Species	mouse
Form	Liquid
Formulation	In PBS, 0.1% BSA, pH 7.5.
Concentration Label	Please refer to vial label for lot-specific concentration
Preservative	None
Comments	Variables associated with assay conditions will dictate the optimal working dilution.
Storage	Avoid freeze/thaw -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Standard Handling
References	Kuro-o, M., et al. 1997. Nature 390, 45. Martin, G.M. and Mian, I.S. 1997. Nature 390, 18.

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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