Millipore Sigma Vibrant Logo

MABF735 Anti-KLRG1 Antibody (mouse), FITC, clone 2F1

This golden syrian hamster monoclonal antibody Anti-KLRG1 (mouse), FITC, clone 2F1 validated for use in IP & Flow Cytometry for the detection of KLRG1.

Anti-KLRG1 Antibody (mouse), FITC, clone 2F1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Gene Symbol: Klrg1, Mafa UniProt Number: O88713
View Products on Sigmaaldrich.com
MABF735
25 µg  
正在检索价格......
无法检索价格。
最小订购数量为倍数
Maximum Quantity is
以订单确认为准 更多信息
您节约了 ()。
 
—
Request Pricing
—
目前缺货 目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余：另行通知
      其余：另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      特卖

       

      联系客户服务

      概述

      Replacement Information

      特卖

      100% Performance Guaranteed

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MIP, FCSHmFITCMonoclonal Antibody
      Description
      Catalogue NumberMABF735
      DescriptionAnti-KLRG1 Antibody (mouse), FITC, clone 2F1
      Alternate Names
      • Killer cell lectin-like receptor subfamily G member 1
      • Mast cell function-associated antigen 2F1
      Background InformationThe 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations.
      References
      Product Information
      FormatFITC
      PresentationPurified Golden Syrian Hamster Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis golden syrian hamster monoclonal antibody Anti-KLRG1 (mouse), FITC, clone 2F1 validated for use in IP & Flow Cytometry for the detection of KLRG1.
      Key Applications
      • Immunoprecipitation
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      Clone2F1
      Concentration0.5 mg/mL
      HostSyrian Hamster
      IsotypeIgG
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Klrg1
      • Mafa
      Purification MethodSize Exclusion Chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThe monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.5 µg of this antibody detected KLRG1 in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsIt is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size25 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      MABF735 04053252965975

      相关产品和应用

      Related Products

      产品目录编号 描述  
      MABF1444 Anti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody 显示价格及库存情况
      MABF1445 Anti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody 显示价格及库存情况
      MABF465 Anti-KLRG1 Antibody (mouse), APC, clone 2F1 显示价格及库存情况
      MABF466 Anti-KLRG1 Antibody (mouse), PE, clone 2F1 显示价格及库存情况
      MABF467 Anti-KLRG1 Antibody (mouse), clone 2F1 显示价格及库存情况
      MABF468 Anti-KLRG1 Antibody (mouse), FITC, clone 2F1 显示价格及库存情况
      MABF733 Anti-KLRG1 Antibody (mouse), APC, clone 2F1 显示价格及库存情况
      MABF734 Anti-KLRG1 Antibody (mouse), PE, clone 2F1 显示价格及库存情况

      种类

      Life Science Research > Antibodies and Assays > Primary Antibodies