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MABF1504 Sigma-AldrichAnti-IL-4 (mouse), APC, clone 11B11 Antibody

This rat monoclonal Anti-IL-4 Antibody (mouse), APC, clone 11B11, Cat. No. MABF1504 is validated for use in Flow Cytometry, for the detection of IL-4.

Anti-IL-4 (mouse), APC, clone 11B11 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Il4, Il-4 UniProt Number: P07750

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
M	FC	R	APC	Monoclonal Antibody

Description
Catalogue Number	MABF1504
Description	Anti-IL-4 (mouse), APC, clone 11B11 Antibody
Alternate Names	Interleukin-4 (IL-4) B-cell IgG differentiation factor B-cell growth factor 1 B-cell stimulatory factor 1 (BSF-1) IGG1 induction factor Lymphocyte stimulatory factor 1 IL-4
Background Information	The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).The 11B11 antibody is widely used for detection of intracellular levels of IL-4 protein by flow cytometry, as well as for analysis of soluble cytokine as measured by ELISA, and in functional assays to neutralization cytokine-receptor interactions.

References

Product Information
Format	APC
Presentation	Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Quality Level	MQ100

Applications
Application	This rat monoclonal Anti-IL-4 Antibody (mouse), APC, clone 11B11, Cat. No. MABF1504 is validated for use in Flow Cytometry, for the detection of IL-4.
Key Applications	Flow Cytometry

Biological Information
Immunogen	Immunogen information for this antibody is proprietary information.
Clone	11B11
Concentration	Please refer to lot specific datasheet.
Host	Rat
Species Reactivity	Mouse
Antibody Type	Monoclonal Antibody
Gene Symbol	Il4 Il-4
Purification Method	Purified by size-exclusion chromatography
UniProt Number	P07750

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.5 μg from a representative lot detected IL-4 in one million C57Bl/6 splenocytes.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt. Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Packaging Information
Material Size	100 μg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABF1504	04055977292206

Documentation

Anti-IL-4 (mouse), APC, clone 11B11 Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-IL-4 (mouse), APC, clone 11B11 Antibody 分析证书

标题	批号
Anti-IL-4 (mouse), APC, clone 11B11 -QVP1505286	QVP1505286
Anti-IL-4 (mouse), APC, clone 11B11 Monoclonal Antibody	VP1704033

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描述

MABF1503

Anti-IL-4 (mouse), APC, clone 11B11 Antibody

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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