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AB9900 Anti-IDO Antibody

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AB9900
100 µg  
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      概述

      Replacement Information

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MELISA, WBRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9900
      Replaces04-1056
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-IDO Antibody
      Alternate Names
      • Indoleamine 2,3-dioxygenase
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      PresentationLiquid on PBS, pH 7.4.
      Quality LevelMQ100
      Applications
      ApplicationAnti-IDO Antibody detects level of IDO & has been published & validated for use in ELISA & WB.
      Key Applications
      • ELISA
      • Western Blotting
      Application NotesWestern blot: 1:2,000-1:5,000 using ECL. Reacts with the ~45 kDa IDO protein. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 with 5% skim milk. Suggested incubation time is 1 hour at room temperature.

      ELISA, direct and indirect: 1:2,000-1:10,000.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenRecombinant mouse IDO.
      HostRabbit
      SpecificityIDO [Indoleamine 2,3-dioxygenase], mouse.
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryGamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.42). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine.[supplied by OMIM]
      Gene Symbol
      • INDO
      • IDO
      • EC 1.13.11.52
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P14902 # Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
      COFACTOR: Binds 1 heme group per subunit.
      SIZE: 403 amino acids; 45326 Da
      SIMILARITY: SwissProt: P14902 ## Belongs to the indoleamine 2,3-dioxygenase family.
      Molecular Weight45 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      AB9900 04053252367113

      Documentation

      Anti-IDO Antibody MSDS

      职位

      物料安全数据表 (MSDS) 

      Anti-IDO Antibody 分析证书

      标题批号
      RABBIT ANTI-IDO (MOUSE) POLYCLONAL ANTIBODY - 2424656 2424656
      RABBIT ANTI-IDO (MOUSE) - 3474907 3474907
      RABBIT ANTI-IDO (MOUSE) - 3821597 3821597
      RABBIT ANTI-IDO (MOUSE) -2519297 2519297
      RABBIT ANTI-IDO (MOUSE) -2792500 2792500
      RABBIT ANTI-IDO (MOUSE) POLYCLONAL ANTIBODY 2929359
      RABBIT ANTI-IDO (MOUSE) POLYCLONAL ANTIBODY - 2168232 2168232
      RABBIT ANTI-IDO (MOUSE) POLYCLONAL ANTIBODY - 2275537 2275537

      参考

      参考概述公共医疗ID
      Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome.
      Gilboa-Geffen, A; Wolf, Y; Hanin, G; Melamed-Book, N; Pick, M; Bennett, ER; Greenberg, DS; Lester, S; Rischmueller, M; Soreq, H
      PloS one  6  e28727  2011

      显示摘要
      22174879 22174879

      相关产品和应用

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      产品目录编号 描述  
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      种类

      Life Science Research > Antibodies and Assays > Primary Antibodies