Millipore Sigma Vibrant Logo

AB15157 Anti-Ghrelin Antibody, active & proform

View Products on Sigmaaldrich.com
AB15157
100 µL  
正在检索价格......
无法检索价格。
最小订购数量为倍数
Maximum Quantity is
以订单确认为准 更多信息
您节约了 ()。
 
Request Pricing
目前缺货
目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余:另行通知
      其余:另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      特卖

       

      联系客户服务

      概述

      Replacement Information

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB15157
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Ghrelin Antibody, active & proform
      References
      Product Information
      FormatSerum
      PresentationLiquid.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Ghrelin Antibody, active & proform is validated for use in WB for the detection of Ghrelin.
      Key Applications
      • Western Blotting
      Application NotesWestern blot: 1:5,000-1:10,000 on extracts from mouse stomach.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      HostRabbit
      SpecificityGhrelin, active & proform. By Western blot the antibody recognizes a band at ~13 kDa using mouse stomach lysate. The band is completed abolished after incubating the antibody with the immunogen peptide.
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryGhrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.[supplied by OMIM]
      Gene Symbol
      • GHRL
      • ghrelin
      • obestatin
      • MTLRP
      Purification MethodSerum
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
      SIZE: 117 amino acids; 12911 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
      PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
      SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      AB15157 04053252338922

      相关产品和应用

      Related Products

      产品目录编号 描述  
      AB9758 Anti-Obestatin Antibody 显示价格及库存情况
      MAB10404 Anti-Ghrelin Antibody, clone 1ML-1D7 显示价格及库存情况

      种类

      Life Science Research > Antibodies and Assays > Primary Antibodies