It appears that your browser has JavaScript disabled.

This Website requires your browser to be JavaScript enabled.

Please enable JavaScript and reload this page.

MABT51 Sigma-AldrichAnti-Galectin-3 Antibody, clone M3/38

Anti-Galectin-3 Antibody, clone M3/38 is an antibody against Galectin-3 for use in WB, IP, IH & IC.

Anti-Galectin-3 Antibody, clone M3/38 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Apoptosis & Cancer Research Sub-Category: BCL2 & Inhibition Gene Symbol: LGALS3, L-31, GAL3, Galectin-3, GALIG, MAC2, GALBP, LGALS2, MAC-2, CBP35 UniProt Number: P16110

View Products on Sigmaaldrich.com

Recommended Products

概述

Replacement Information

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB, IP, IHC, ICC	R	Purified	Monoclonal Antibody

Description
Catalogue Number	MABT51
Description	Anti-Galectin-3 Antibody, clone M3/38
Alternate Names	lectin, galactoside-binding, soluble, 3 Mac-2 antigen Carbohydrate-binding protein 35 galectin-3 Galactose-specific lectin 3 Laminin-binding protein Lectin L-29 IgE-binding protein Galactoside-binding protein
Background Information	Galectin-3 belongs to the galectin gene family defined by the specificity of a carbohydrate recognition domain (CRD) for Gal/Lac and expression is usually elevated in a wide range of neoplastic cell types. The galectin CRD consists of 135 amino acids. Galectin-3 has been shown to effect tumor development and progression.

References

Product Information
Format	Purified
Control	HeLa cell lysate
Presentation	Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-Galectin-3 Antibody, clone M3/38 is an antibody against Galectin-3 for use in WB, IP, IH & IC.
Key Applications	Western Blotting Immunoprecipitation Immunohistochemistry Immunocytochemistry
Application Notes	Western Blot Analysis: 1:50,000 dilution from a previous lot detected Galectin-3 in 10 µg of NIH/3T3 cell lysate. Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP. (Springer, T., et al. (1981). THE JOURNAL OF BIOLOGICACHLE MISTRY. 256(8):3833-3839.) Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Gasbarri, A., et al. (1999). Journal of Clinical Oncology. 17(11):3494-3502.) Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. (Gasbarri, A., et al. (1999). Journal of Clinical Oncology. 17(11):3494-3502.)

Biological Information
Immunogen	Plasma membrane glycoproteins corresponding to mouse Galectin-3.
Clone	M3/38
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rat
Isotype	IgG2aκ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001139425
Gene Symbol	LGALS3 L-31 GAL3 Galectin-3 GALIG MAC2 GALBP LGALS2 MAC-2 CBP35
Purification Method	Protein G Purified
UniProt Number	P16110
UniProt Summary	FUNCTION: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). SUBUNIT STRUCTURE: Probably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA. SUBCELLULAR LOCATION: Nucleus. Note: Cytoplasmic in adenomas and carcinomas (By similarity). May be secreted by a non-classical secretory pathway and associate with the cell surface. TISSUE SPECIFICTY: The highest levels are found in activated macrophages. SEQUENCE SIMILARITIES: Contains 1 galectin domain.
Molecular Weight	~28 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 1:50,000 dilution of this antibody detected Galectin-3 in 10 µg of HeLa cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	50 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABT51	04053252290985

Documentation

Anti-Galectin-3 Antibody, clone M3/38 MSDS

职位
物料安全数据表 (MSDS)

Anti-Galectin-3 Antibody, clone M3/38 分析证书

标题	批号
Anti-Galectin-3, clone M3/38	2476943
Anti-Galectin-3, clone M3/38	2474212
Anti-Galectin-3, clone M3/38 - 2135135	2135135
Anti-Galectin-3, clone M3/38 - 1991862	1991862
Anti-Galectin-3, clone M3/38 - 2225189	2225189
Anti-Galectin-3, clone M3/38 - 2327014	2327014
Anti-Galectin-3, clone M3/38 - 2531557	2531557
Anti-Galectin-3, clone M3/38 - 3174817	3174817
Anti-Galectin-3, clone M3/38 - 3524845	3524845
Anti-Galectin-3, clone M3/38 - 3613019	3613019

相关产品和应用

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

最近查看的内容