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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABN450 Sigma-AldrichAnti-GCM2 Antibody, clone 8A10.1

This Anti-GCM2 Antibody, clone 8A10.1 is validated for use in Western Blotting for the detection of GCM2.

Anti-GCM2 Antibody, clone 8A10.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: GCMB UniProt Number: O75603

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABN450
Description	Anti-GCM2 Antibody, clone 8A10.1
Alternate Names	hGCMb Chorion-specific transcription factor GCMb GCM2 GCM 2 GCM-2 GCM motif protein 2 Glial cells missing homolog 2
Background Information	GCM2 is a nuclear protein that is involved in transcription regulation of many genes including ones important in parathyroid metabolism and development. Glial cells missing homolog 2 or GCM2 is expressed predominately in the pharyngeal pouches and, at later stages, in the developing and mature parathyroid glands. In humans, loss of GCM2 function, either through recessive apomorphic mutations or dominant inhibitor mutations in the human GCM2 gene, leads to isolated hypoparathyroidism. GCM2 expression is continued in the adult parathyroid at high levels and appears to be important in calcium sensing and calcium receptor expression in adult parathyroid cells.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	This Anti-GCM2 Antibody, clone 8A10.1 is validated for use in Western Blotting for the detection of GCM2.
Key Applications	Western Blotting

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to Human GCM2.
Clone	8A10.1
Concentration	0.5 mg/mL
Host	Mouse
Isotype	IgMκ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_004743
Gene Symbol	GCMB
UniProt Number	O75603
Molecular Weight	~ 58 kDa observed. An uncharacterized band appears at ~110 kDa in some lysates.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in SH-SY5Y cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected GCM2 in 10 µg of SH-SY5Y cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABN450	04055977112726

Documentation

Anti-GCM2 Antibody, clone 8A10.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-GCM2 Antibody, clone 8A10.1 分析证书

标题	批号
Anti-GCM2, clone 8A10.1	Q2476159
Anti-GCM2, clone 8A10.1 - 3745893	3745893

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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