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MABN498 Anti-GABA(A)R BETA 1 Protein Antibody, clone N96/55

This GABA(A)R antibody is validated for use in IHC & WB for the detection of the GABA(A)R protein.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Signaling Neuroscience Gene Symbol: Gabrb1 UniProt Number: P50571
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MABN498
100 µg  
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      概述

      Replacement Information

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      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, MIHC, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN498
      DescriptionAnti-GABA(A)R BETA 1 Protein Antibody, clone N96/55
      Alternate Names
      • Gamma-aminobutyric acid receptor subunit beta-1
      • GABA(A) receptor subunit beta-1
      Background InformationGABA(A)R, beta-1 is a subunit of the GABA receptor. GABA receptors belong to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid or GABA is the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA receptors play an important role in transmembrane ion transport, excitability and synaptic transmission.
      References
      Product Information
      FormatPurified
      Control
      • Rat hippocampus tissue
      PresentationPurified monoclonal mouse IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis GABA(A)R antibody is validated for use in IHC & WB for the detection of the GABA(A)R protein.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat olfactory lobe tissue.

      Western Blot Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat brain membrane tissue lysate.

      Immunohistochemistry Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.
      Biological Information
      ImmunogenFusion protein corresponding to mouse GABA(A)R, BETA 1.
      CloneN96/55
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody does not cross react with GABA-A-R, Beta 2 Protein or GABA-A-R, Beta 3 Protein.
      IsotypeIgG1κ
      Species Reactivity
      • Rat
      • Mouse
      Species Reactivity NoteDemonstrated to react with Rat and Mouse. Other homologies: Human (95% sequence homology).
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Gabrb1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~55 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in rat hippocampus tissue.

      Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      MABN498 04053252850936