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MABC1036 Anti-EphA7 Antibody, clone 2F3.1

Anti-EphA7 Antibody, clone 2F3.1 is an antibody against EphA7 for use in Western Blotting.

Anti-EphA7 Antibody, clone 2F3.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Cytokines & Cytokine Receptors Gene Symbol: EPHA7, EHK3, HEK11 UniProt Number: Q15375
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MABC1036
100 μg  
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      概述

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      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC1036
      DescriptionAnti-EphA7 Antibody, clone 2F3.1
      Alternate Names
      • Ephrin type-A receptor 7
      • EHK-3
      • EK11
      • EPH homology kinase 3
      • EPH-like kinase 11
      • hEK11
      • Receptor protein-tyrosine kinase HEK11
      • Tyrosine-protein kinase receptor EHK-3
      Background InformationEphrin type-A receptor 7 (EC 2.7.10.1; UniProt Q15375; also known as EHK-3, EK11, EPH homology kinase 3, EPH-like kinase 11, hEK11, Receptor protein-tyrosine kinase HEK11, Tyrosine-protein kinase receptor EHK-3) is encoded by the EPHA7 (also known as EHK3, HEK11) gene (Gene ID 2045) in human. EphA7 belongs to the ephrin receptor family of receptor tyrosine kinases that are activated upon ephrin binding. Ephrin receptor signaling plays important roles in embryonic development, tissue boundaries formation, angiogenesis, stem cell differentiation, and cancer. There exist nine type-A (EphA1-8 and EphA10) and five type-B (EphB1-4 and EphB6) ephrin receptors in human. EphA7 is initially produced with a signal peptide (a.a. 1-27) sequence, the removal of which yields the mature protein with a large extracellular (a.a. 28-555) region, followed by a transmembrane segment (a.a. 556-576) and a cytoplasmic region (a.a. 577-998) that contains the kinase domain (a.a. 633-894).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-EphA7 Antibody, clone 2F3.1 is an antibody against EphA7 for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant extracellular N-terminal fragment of human EphA7.
      EpitopeExtracellular domain.
      Clone2F3.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityExpected to react with all five spliced isoforms of human EphA7 reported by UniProt (Q15375).
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EPHA7
      • EHK3
      • HEK11
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~120 kDa observed. 112.1 kDa (isoform 1; EPHA7-FL), 111.5 kDa (isoform 2), 31.83 kDa (isoform 3), 111.6 kDa (isoform 4), and 50.52 kDa (isoform 5; EPHA7-S) calculated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in MCF-7 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected EphA7 in 10 µg of MCF-7 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      MABC1036 04055977330359