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MABD398 Anti-DAX-1, clone 2F4 Antibody

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MABD398
100 µL  
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      概述

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IHCMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABD398
      Replaces04-445
      DescriptionAnti-DAX-1, clone 2F4 Antibody
      Alternate Names
      • Dax1
      • Nuclear receptor subfamily 0 group B member 1
      • DSS-AHC critical region on the X chromosome protein 1
      • Nuclear receptor DAX-1
      • AHC
      Background InformationDAX-1 is an orphan nuclear receptor and is required for the normal development of the hypothalamic-pituitary-adrenal-gonadal axis formation. Defects in DAX-1 are the cause of X-linked adrenal hypoplasia congenital (XL-AHC); also known as X-linked Addison disease (AHX). DAX-1 also has a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency by acting as a negative regulator of Oct3/4 in ES cells.
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1κ Ascites with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-DAX-1, clone 2F4 Antibody is validated for use in Western Blotting and Immunocytochemistry and Immunohistochemistry for the detection of DAX-1.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesAnti-DAX-1, clone 2F4, has been shown to work in Immunocytochemical (Lehmann et al., 2009) and Immunohistochemical (Ehrlund et al., 2013) analysis.
      Biological Information
      ImmunogenLinear peptide corresponding to Human DAX-1 (amino acids 135-166).
      Clone2F4
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NR0B1
      • DAX1
      • AHC
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~ 52 kDa observed
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in a Dax-1 overexpressing HEK293 transfected cell line. Western Blot Analysis: A 1:1000 dilution of this antibody detected DAX-1 in a DAX-1 overexpressing HEK293 transfected cell line.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      产品目录编号 GTIN
      MABD398 04053252986512