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			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

236002 Sigma-AldrichAnti-COX2, C-Terminal Rabbit pAb

This Anti-COX2, C-Terminal Rabbit pAb is validated for use in Immunoblotting, ELISA for the detection of COX2, C-Terminal.

Anti-COX2, C-Terminal Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Anti-Cyclooxygenase-2, Anti-PGHS-2, Anti-Prostaglandin H Synthase-2

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概述

Replacement Information

重要规格表

Species Reactivity	Host	Antibody Type
B, H, M, R, Sh	Rb	Polyclonal Antibody

价格及供货情况

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Description
Overview	Recognizes COX2. Does not cross-react with COX1.
Catalogue Number	236002
Brand Family	Calbiochem®
Synonyms	Anti-Cyclooxygenase-2, Anti-PGHS-2, Anti-Prostaglandin H Synthase-2

References
References	Hla, T., and Neilson, K. 1992. Proc. Natl. Acad. Sci. USA 89, 7384.

Product Information
Form	Liquid
Formulation	In PBS, 0.1% BSA, pH 7.4.
Preservative	≤0.1% sodium azide
Quality Level	MQ100

Applications
Key Applications	Enzyme-Linked Immunosorbent Assay Immunoblotting (Western Blotting)
Application Notes	Immunoblotting (1-10 µg/ml, chemiluminescence) ELISA (1:10,000-1:100,000)
Application Comments	Does not cross-react with COX1. Variables associated with assay conditions will dictate the optimal working dilution.

Biological Information
Immunogen	a synthetic peptide corresponding to a 17-amino acid sequence near the C-terminus of human COX2
Immunogen	Human
Host	Rabbit
Isotype	IgG
Species Reactivity	Bovine Human Mouse Rat Sheep
Antibody Type	Polyclonal Antibody
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	-20°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
236002-50UGCN	04055977217094

Documentation

Anti-COX2, C-Terminal Rabbit pAb MSDS

职位
物料安全数据表 (MSDS)

Anti-COX2, C-Terminal Rabbit pAb 分析证书

标题	批号
236002	输入批号

参考

参考信息概述
Hla, T., and Neilson, K. 1992. Proc. Natl. Acad. Sci. USA 89, 7384.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	26-July-2007 RFH
Synonyms	Anti-Cyclooxygenase-2, Anti-PGHS-2, Anti-Prostaglandin H Synthase-2
Application	Immunoblotting (1-10 µg/ml, chemiluminescence) ELISA (1:10,000-1:100,000)
Description	Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~72 kDa COX2 protein.
Background	COX proteins are membrane-associated heme proteins that have cyclooxygenase and peroxidase activities. These enzymes are targets of NSAID (Nonsteroidal anti-inflammatory drugs) such as aspirin. Prostaglandins (PGs) formed by the enzymatic activity of COX1 are primarily involved in the regulation of homeostatic functions throughout the body, whereas PGs formed by COX2 primarily mediate pain, fever, and inflammation. COX2 is induced by a wide variety of stimuli and was initially identified as an immediate-early growth response gene. In addition, COX2 expression is markedly increased in 85-90% of human colorectal adenocarcinomas, whereas COX1 levels remain unchanged. COX2 may be involved in angiogenesis, as new angiogenic endothelial cells express the inducible COX2 while normal blood vessels express COX1.
Host	Rabbit
Immunogen species	Human
Immunogen	a synthetic peptide corresponding to a 17-amino acid sequence near the C-terminus of human COX2
Isotype	IgG
Species	bovine, human, mouse, rat, sheep
Form	Liquid
Formulation	In PBS, 0.1% BSA, pH 7.4.
Concentration Label	Please refer to vial label for lot-specific concentration
Preservative	≤0.1% sodium azide
Comments	Does not cross-react with COX1. Variables associated with assay conditions will dictate the optimal working dilution.
Storage	Avoid freeze/thaw -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Standard Handling
References	Hla, T., and Neilson, K. 1992. Proc. Natl. Acad. Sci. USA 89, 7384.

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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