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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABC664 Sigma-AldrichAnti-CLEC2A Antibody, clone 8D2.1

This Anti-CLEC2A Antibody, clone 8D2.1 is validated for use in Western Blotting for the detection of CLEC2A.

Anti-CLEC2A Antibody, clone 8D2.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: CLEC2A, KACL UniProt Number: Q6UVW9

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABC664
Description	Anti-CLEC2A Antibody, clone 8D2.1
Alternate Names	C-type lectin domain family 2 member A Keratinocyte-associated C-type lectin KACL Proliferation-induced lymphocyte-associated receptor PILAR CLEC2A
Background Information	C-type lectin domain family 2 member A (CLEC2A) is also called proliferation-induced lymphocyte-associated receptor (PILAR) and Keratinocyte-associated C-type lectin (KACL). CLEC2A is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Modulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer. CLEC2A is associated with expansion of TCR-stimulated T-cells, modulates the capacity of T-cells to home to lymph nodes through SELL, and facilitates immune recognition of keratinocytes by stimulating natural killer cell mediated cytotoxicity.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	This Anti-CLEC2A Antibody, clone 8D2.1 is validated for use in Western Blotting for the detection of CLEC2A.
Key Applications	Western Blotting

Biological Information
Immunogen	KLH-conjugated linear peptide corresponding to the extracellular domain of human CLEC2A.
Epitope	Extracellular domain
Clone	8D2.1
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001124183
Gene Symbol	CLEC2A KACL
Purification Method	Protein G Purified
UniProt Number	Q6UVW9
Molecular Weight	~18 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in Raji cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected CLEC2A in 200 µg of Raji cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABC664	04053252978807

Documentation

Anti-CLEC2A Antibody, clone 8D2.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-CLEC2A Antibody, clone 8D2.1 分析证书

标题	批号
Anti-CLEC2A, clone 8D2.1 - Q2436818	Q2436818

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产品目录编号

描述

ABC328

Anti-CLEC2A Antibody

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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