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MABF546 Sigma-AldrichAnti-CD25 Antibody (human), PE, clone BC96

This mouse monoclonal antibody Anti-CD25 (human), PE & clone BC96 validated for use in Flow Cytometry for the detection of CD25.

Anti-CD25 Antibody (human), PE, clone BC96 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Inflammation & Immunology Gene Symbol: IL2RA UniProt Number: P01589

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	FC	M	PE	Monoclonal Antibody

Description
Catalogue Number	MABF546
Description	Anti-CD25 Antibody (human), PE, clone BC96
Alternate Names	Interleukin-2 receptor subunit alpha IL-2 receptor subunit alpha IL-2-RA IL-2R subunit alpha IL2-RA TAC antigen p55 CD antigen CD25
Background Information	The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, althoµgh with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells. The BC96 antibody may be used as a marker for expression of CD25 during T and B cell development, on activated mature T and B cells, and for its expression at high levels on natural T regulatory cells (nTreg cells) in the thymus or periphery, and on “induced” peripheral Tregs. This antibody is cross-reactive with CD25 in several non-human species, including Baboon, Chimpanzee, Cynomolgus and Rhesus.

References

Product Information
Format	PE
Presentation	Purified Mouse Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
Quality Level	MQ100

Applications
Application	This mouse monoclonal antibody Anti-CD25 (human), PE & clone BC96 validated for use in Flow Cytometry for the detection of CD25.
Key Applications	Flow Cytometry

Biological Information
Immunogen	Immunogen information for this antibody is proprietary information.
Clone	BC96
Concentration	5 µL (0.06 µg)/test
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Gene Symbol	IL2RA
Purification Method	Size Exclusion Chromatography
UniProt Number	P01589

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.06 µg of this antibody detected CD25 in one million human peripheral blood lymphocytes.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Packaging Information
Material Size	25 tests

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABF546	04053252963124

Documentation

Anti-CD25 Antibody (human), PE, clone BC96 MSDS

职位
物料安全数据表 (MSDS)

Anti-CD25 Antibody (human), PE, clone BC96 分析证书

标题	批号
Anti-CD25 (human), PE, clone BC96 - TN14020501	TN14020501

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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