Millipore Sigma Vibrant Logo

MABF1512 Anti-CD127 (IL-7Ra) (mouse), violetFluor™ 450, clone A7R34 Antibody

Anti-CD127 (IL-7Ra) (mouse), violetFluor™ 450, clone A7R34 Antibody detects level of CD127 and has been published and validated for use in Flow Cytometry.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Il7r UniProt Number: P16872
View Products on Sigmaaldrich.com
MABF1512
100 μg  
正在检索价格......
无法检索价格。
最小订购数量为倍数
Maximum Quantity is
以订单确认为准 更多信息
您节约了 ()。
 
—
Request Pricing
—
目前缺货 目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余：另行通知
      其余：另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      特卖

       

      联系客户服务

      概述

      Replacement Information

      特卖

      100% Performance Guaranteed

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFCRvioletFluor™ 450Monoclonal Antibody
      Description
      Catalogue NumberMABF1512
      DescriptionAnti-CD127 (IL-7Ra) (mouse), violetFluor™ 450, clone A7R34 Antibody
      Alternate Names
      • Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha or IL-7R subunit alpha or IL-7R-alpha or IL-7RA)
      • CD127
      • CD127 (IL-7Ra)
      Background InformationThe A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).
      References
      Product Information
      FormatvioletFluor™ 450
      PresentationPurified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
      Quality LevelMQ100
      Applications
      ApplicationAnti-CD127 (IL-7Ra) (mouse), violetFluor™ 450, clone A7R34 Antibody detects level of CD127 and has been published and validated for use in Flow Cytometry.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      CloneA7R34
      ConcentrationPlease refer to lot specific datasheet.
      HostRat
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Il7r
      Purification MethodPurified by size-exclusion chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.5 μg from a representative lot detected CD127 (IL-7Ra) in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      MABF1512 04055977292268

      相关产品和应用

      Related Products

      产品目录编号 描述  
      MABF1511 Anti-CD127 (IL-7Ra) (mouse), violetFluor™ 450, clone A7R34 Antibody 显示价格及库存情况

      种类

      Life Science Research > Antibodies and Assays > Primary Antibodies