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MABN124 Sigma-AldrichAnti-ATF-3 Antibody, clone 13A5.1

Anti-ATF-3 Antibody, clone 13A5.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
小册子

Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: ATF3 UniProt Number: P18847

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概述

Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB	Human Recombinant	Purified	Monoclonal Antibody

Description
Catalogue Number	MABN124
Description	Anti-ATF-3 Antibody, clone 13A5.1
Alternate Names	Cyclic AMP-dependent transcription factor ATF-3 Activating transcription factor 3 cAMP-dependent transcription factor ATF-3
Background Information	Cyclic AMP-dependent transcription factor ATF-3 (UniProt P18847; also known as Activating transcription factor 3, cAMP-dependent transcription factor ATF-3) is encoded by the ATF3 gene (Gene ID 467) in human. ATF-3 belongs to the ATF/cAMP-responsive element-binding protein family of basic leucine zipper-type transcription factors. ATF-3 is markedly induced and functions as either a transcriptional activator or repressor in response to LPS, cytokines, hormones, DNA damage, and ER stress in various cell types. ATF3 plays key roles in atherosclerosis and hyperlipidemia, and is reported to negatively regulate the differentiation of adipocyte, chondrocyte, and osteoblast. ATF-3 dysfunction is closely related to various inflammatory diseases and cancer.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Key Applications	Western Blotting
Application Notes	Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ATF-3 in 10 µg of RAW264.7 cell lysate.

Biological Information
Immunogen	GST-tagged recombinant human ATF-3 fragment.
Clone	13A5.1
Concentration	Please refer to lot specific datasheet.
Host	Human Recombinant
Specificity	Expected to react with spliced isoforms 1 and 5 (UniProt P18847-1 and P18847-5). Reactivity toward spliced isoforms 2, 3, and 4 (UniProt P18847-2 through P18847-4) of human ATF-3 has not been determined.
Isotype	IgG2bκ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001665
Gene Symbol	ATF3
Purification Method	Protein G Purified
UniProt Number	P18847
Molecular Weight	~19 kDa observed.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in THP-1 cell lysate. Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ATF-3 in 10 µg of THP-1 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABN124	04055977311884

Documentation

Anti-ATF-3 Antibody, clone 13A5.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-ATF-3 Antibody, clone 13A5.1 分析证书

标题	批号
Anti-ATF-3, clone 13A5.1 - 3425386	3425386
Anti-ATF-3, clone 13A5.1 - 4136257	4136257

小册子

标题
Neuroscience Solutions for productive research

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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