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ABS184 Sigma-AldrichAnti-AMPylated Tyrosine Antibody

Anti-AMPylated Tyrosine Antibody detects level of AMPylated Tyrosine & has been published & validated for use in Western Blotting.

Anti-AMPylated Tyrosine Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
小册子

Research Category: Signaling Research Sub-Category: General Post-translation Modification

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概述

Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB	Rb	Serum	Polyclonal Antibody

Description
Catalogue Number	ABS184
Description	Anti-AMPylated Tyrosine Antibody
Alternate Names	AMPylated Tyrosine
Background Information	AMPylation is a reversible post-translational modification in which adenosine monophosphate (AMP) derived from ATP is added to threonine and tyrosine (and possibly serine) residues on target proteins. This modification is created by proteins containing Fic (filamentation induced by cyclic adenosine monophosphate) domains, which are present in both prokaryotic and eukaryotic cells. In mammals, the HYPE protein is the most widely known Fic-containing protein and the precise function of its AMPylated targets is not yet clear. However, bacterial cells possess numerous Fic-domain proteins that modify and disable protein targets in host cells, thereby suppressing signaling pathways and increasing the robustness of pathogenic infections. The Vibrio parahaemolyticus VopS protein, for instance, disrupts the function of Rho guanine triphosphatases, and eventually disrupts the actin cytoskeleton.

References

Product Information
Format	Serum
Control	Rac1, AMPylated in vitro
Presentation	Rabbit polyclonal serum containing 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-AMPylated Tyrosine Antibody detects level of AMPylated Tyrosine & has been published & validated for use in Western Blotting.
Key Applications	Western Blotting

Biological Information
Host	Rabbit
Specificity	This antibody recognizes AMPylated Tyrosines.
Isotype	IgG
Species Reactivity	Human
Species Reactivity Note	Demonstrated to react with Human. Broad species reactivity expected, as AMPylation is evolutionarily conserved.
Antibody Type	Polyclonal Antibody
Purification Method	Unpurified
Molecular Weight	~21 kDa observed. Molecular weights will vary based on the protein being AMPylated.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blot in Rac1, AMPylated in vitro. Western Blot Analysis: A 1:1,000 dilution of this antibody detected AMPylated Tyrosine on 10 ng of Rac1, AMPylated in vitro.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
ABS184	04053252439247

Documentation

Anti-AMPylated Tyrosine Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-AMPylated Tyrosine Antibody 分析证书

标题	批号
Anti-AMPylated Tyrosine - 2450771	2450771
Anti-AMPylated Tyrosine - 2341112	2341112
Anti-AMPylated Tyrosine - 2512049	2512049
Anti-AMPylated Tyrosine - 3216004	3216004
Anti-AMPylated Tyrosine - 3839094	3839094
Anti-AMPylated Tyrosine - Q2005661	Q2005661
Anti-AMPylated Tyrosine -2890952	2890952
Anti-AMPylated Tyrosine Polyclonal Antibody	3091980
Anti-AMPylated Tyrosine Polyclonal Antibody	3041062
Anti-AMPylated Tyrosine Polyclonal Antibody	2929154

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标题
New Products: Volume 3, 2012

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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