Millipore Sigma Vibrant Logo

07-208 Anti-AIF (Apoptosis Inducing Factor) Antibody

Anti-AIF (Apoptosis Inducing Factor) Antibody detects level of AIF (Apoptosis Inducing Factor) & has been published & validated for use in WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: AIFM1, MGC111425, PDCD8, AIF UniProt Number: O95831
View Products on Sigmaaldrich.com
07-208
200 µg  
正在检索价格......
无法检索价格。
最小订购数量为倍数
Maximum Quantity is
以订单确认为准 更多信息
您节约了 ()。
 
—
Request Pricing
—
目前缺货 目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余：另行通知
      其余：另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      特卖

       

      联系客户服务

      概述

      Replacement Information

      特卖

      100% Performance Guaranteed

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBRbPurifiedPolyclonal Antibody
      Description
      Catalogue Number07-208
      Replaces04-430
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-AIF (Apoptosis Inducing Factor) Antibody
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
      Quality LevelMQ100
      Applications
      ApplicationAnti-AIF (Apoptosis Inducing Factor) Antibody detects level of AIF (Apoptosis Inducing Factor) & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      Immunogenpeptide corresponding to amino acids 593-606 of human Apoptosis Inducing Factor, AIF (C-KDGEQHEDLNEVAK), containing a N-terminal cysteine
      HostRabbit
      SpecificityAIF
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
      Gene Symbol
      • AIFM1
      • MGC111425
      • PDCD8
      • AIF
      Purification MethodProtein A chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O95831 # Probable oxidoreductase that acts as a caspase- independent mitochondrial effector of apoptotic cell death. Extramitochondrial AIF induces nuclear chromatin condensation and large scale DNA fragmentation (in vitro).
      COFACTOR: FAD.
      SIZE: 613 amino acids; 66901 Da
      SUBUNIT: Binds to DNA in a sequence-independent manner.
      SUBCELLULAR LOCATION: Mitochondrion intermembrane space. Nucleus. Note=Translocated to the nucleus upon induction of apoptosis.
      SIMILARITY: SwissProt: O95831 ## Belongs to the FAD-dependent oxidoreductase family.
      Molecular Weight57kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on a mouse liver preparation
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      07-208 04053252336416

      相关产品和应用

      Related Products

      产品目录编号 描述  
      AB16501 Anti-AIF Antibody, internal domain 显示价格及库存情况
      AB16502 Anti-AIF Antibody, NT 显示价格及库存情况

      种类

      Life Science Research > Antibodies and Assays > Primary Antibodies