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MABN287 Sigma-AldrichAnti-ABCA4 Antibody, clone 5D7.1

Anti-ABCA4 Antibody, clone 5D7.1 | MABN287 is an antibody against ABCA4 Antibody for use in Western Blotting, Immunohistochemistry (Paraffin).

Anti-ABCA4 Antibody, clone 5D7.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: ABCA4, ABCR UniProt Number: P78363

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IH(P)	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABN287
Description	Anti-ABCA4 Antibody, clone 5D7.1
Alternate Names	Retinal-specific ATP-binding cassette transporter ATP-binding cassette sub-family A member 4 RIM ABC transporter RIM protein RmP Stargardt disease protein
Background Information	Retinal-specific ATP-binding cassette transporter encoded by the gene ABCA4 plays a critical role in the transport of retinoid substrates from the extracellular or intradiscal rod cell membranes to the cytoplasmic membrane surface for processing ultimately into vitamin A and then transferred to the retinal pigment epithelium where it is converted to 11-cis-retinal that active component needed for vision. ABCA4 is localized to the outer segments of rods and cones with a million copies per photoreceptor. ABCA4 is retinal specific protein. Mutations in ABCA4 are linked to several eye-related genetic diseases, such as forms of macular degeneration called Stargardt disease and ARMD2, as well as Retinitis pigmentosa 19, and Cone-rod dystrophy 3.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-ABCA4 Antibody, clone 5D7.1 \| MABN287 is an antibody against ABCA4 Antibody for use in Western Blotting, Immunohistochemistry (Paraffin).
Key Applications	Western Blotting Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected ABCA4 in human retina tissue.

Biological Information
Immunogen	Recombinant protein corresponding to human ABCA4.
Clone	5D7.1
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_000341
Gene Symbol	ABCA4 ABCR
Purification Method	Protein G Purified
UniProt Number	P78363
Molecular Weight	~275 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in Y79 cell lysate. Western Blotting Analysis: 5.0 µg/mL of this antibody detected ABCA4 in 200 µg of Y79 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABN287	04055977127003

Documentation

Anti-ABCA4 Antibody, clone 5D7.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-ABCA4 Antibody, clone 5D7.1 分析证书

标题	批号
Anti-ABCA4, clone 5D7.1 - 3225731	3225731
Anti-ABCA4, clone 5D7.1 - 3453674	3453674
Anti-ABCA4, clone 5D7.1 -Q2502719	Q2502719

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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