Millipore Sigma Vibrant Logo

05-23-0101 Angiotensin II, Human - CAS 4474-91-3 - Calbiochem

概述

Replacement Information

重要规格表

CAS #Empirical Formula
4474-91-3C₅₀H₇₁N₁₃O₁₂

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
05-23-0101-1MGCN
正在查询供货情况......
目前缺货
目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余:另行通知
      其余:另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      塑胶安瓿;塑胶针药瓶 1 mg
      正在检索价格......
      无法检索价格。
      最小订购数量为倍数
      Maximum Quantity is
      以订单确认为准 更多信息
      您节约了 ()。
       
      Request Pricing
      05-23-0101-25MGCN
      正在查询供货情况......
      目前缺货
目前缺货
      有货 
      停产
      少量现货
      供货情况有待确认
        其余:另行通知
          其余:另行通知
          另行通知
          联系客户服务
          Contact Customer Service

          玻璃瓶 25 mg
          正在检索价格......
          无法检索价格。
          最小订购数量为倍数
          Maximum Quantity is
          以订单确认为准 更多信息
          您节约了 ()。
           
          Request Pricing
          05-23-0101-5MGCN
          正在查询供货情况......
          目前缺货
目前缺货
          有货 
          停产
          少量现货
          供货情况有待确认
            其余:另行通知
              其余:另行通知
              另行通知
              联系客户服务
              Contact Customer Service

              塑胶安瓿;塑胶针药瓶 5 mg
              正在检索价格......
              无法检索价格。
              最小订购数量为倍数
              Maximum Quantity is
              以订单确认为准 更多信息
              您节约了 ()。
               
              Request Pricing
              Description
              OverviewPlays an important role in the regulation of blood pressure. Stimulates the release of aldosterone from the adrenal gland. Inhibits adenylate cyclase activity in spontaneously hypertensive rats. Has strong vasoconstrictive effects. Increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase. Also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons. Activates JAK2 in smooth muscle cells. Activates p125FAK and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. Also activates p60c-src as well as ERK1/2, JNK, and p38 MAP Kinase in vascular smooth muscle cells.
              Catalogue Number05-23-0101
              Brand Family Calbiochem®
              SynonymsDRVYIHPF
              References
              ReferencesZhu, M., et al. 2000. J. Neurophysiol. 84, 2494.
              Natarajan, R., et al. 1999. Hypertension 33, 378.
              Mazzolai, L., et al. 1998. Hypertension 31, 1324.
              Earp, H.S., et al. 1995. J. Biol. Chem. 270, 28440.
              Ishida, M., et al. 1995. Circ. Res. 77, 1053.
              Vyas, S.J., and Jackson, E.K. 1995. J. Pharmacol. Exp. Ther. 273, 768.
              Product Information
              CAS number4474-91-3
              ATP CompetitiveN
              FormWhite to off-white solid
              Hill FormulaC₅₀H₇₁N₁₃O₁₂
              Chemical formulaC₅₀H₇₁N₁₃O₁₂
              Hygroscopic Hygroscopic
              ReversibleN
              Sold on the basis of peptide contentY
              Quality LevelMQ100
              Applications
              Biological Information
              Primary Targetadenylate cyclase activity
              Purity≥98% by HPLC
              Physicochemical Information
              Cell permeableN
              Peptide ContentY
              Peptide SequenceH-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSBW2165000
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              产品目录编号 GTIN
              05-23-0101-1MGCN 04055977206906
              05-23-0101-25MGCN 04055977206913
              05-23-0101-5MGCN 04055977206920

              Documentation

              Angiotensin II, Human - CAS 4474-91-3 - Calbiochem MSDS

              职位

              物料安全数据表 (MSDS) 

              Angiotensin II, Human - CAS 4474-91-3 - Calbiochem 分析证书

              标题批号
              05-23-0101

              参考

              参考信息概述
              Zhu, M., et al. 2000. J. Neurophysiol. 84, 2494.
              Natarajan, R., et al. 1999. Hypertension 33, 378.
              Mazzolai, L., et al. 1998. Hypertension 31, 1324.
              Earp, H.S., et al. 1995. J. Biol. Chem. 270, 28440.
              Ishida, M., et al. 1995. Circ. Res. 77, 1053.
              Vyas, S.J., and Jackson, E.K. 1995. J. Pharmacol. Exp. Ther. 273, 768.
              数据表

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision12-May-2008 JSW
              SynonymsDRVYIHPF
              DescriptionFunctions in blood pressure maintenance. Stimulates the release of aldosterone from the adrenal gland. Has strong vasoconstrictive effects. Increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase. Activates JAK2 in smooth muscle cells. Activates p125FAK and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. Also activates pp60c-src in vascular smooth muscle cells. Inhibits adenylate cyclase activity in spontaneously hypertensive rats.
              FormWhite to off-white solid
              CAS number4474-91-3
              RTECSBW2165000
              Chemical formulaC₅₀H₇₁N₁₃O₁₂
              Peptide SequenceH-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
              Purity≥98% by HPLC
              Solubility5% acetic acid (1 mg/ml) or H₂O (1 mg/ml)
              Storage -20°C
              Hygroscopic
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
              Toxicity Standard Handling
              Merck USA index14 651
              ReferencesZhu, M., et al. 2000. J. Neurophysiol. 84, 2494.
              Natarajan, R., et al. 1999. Hypertension 33, 378.
              Mazzolai, L., et al. 1998. Hypertension 31, 1324.
              Earp, H.S., et al. 1995. J. Biol. Chem. 270, 28440.
              Ishida, M., et al. 1995. Circ. Res. 77, 1053.
              Vyas, S.J., and Jackson, E.K. 1995. J. Pharmacol. Exp. Ther. 273, 768.