Millipore Sigma Vibrant Logo

172060 Andrographolide - CAS 5508-58-7 - Calbiochem

概述

重要规格表

CAS #Empirical Formula
5508-58-7C₂₀H₃₀O₅

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
172060-50MGCN
目前缺货
目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余:另行通知
      其余:另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      塑胶安瓿;塑胶针药瓶 50 mg
      无法检索价格。
      最小订购数量为倍数
      Maximum Quantity is
      以订单确认为准 更多信息
      您节约了 ()。
       
      Request Pricing
      Description
      OverviewA bicyclic diterpenoid lactone that displays anti-viral, anti-inflammatory, anti-apoptotic, and anti-hyperglycemic properties. Acts as an irreversible antagonist of NF-κB and AP-1 (IC50 ≤ 15 µM) activation, and prevents in vitro and in vivo T cell activation. Exerts no effect on IκBα degradation, p50 and p65 nuclear translocation. Inhibits iNOS and Mac-1 expressions and ROS production, and prevents endotoxin shock in mouse model. Further, reported to activate PI 3K/Akt pathway.
      Catalogue Number172060
      Brand Family Calbiochem®
      SynonymsAndro
      References
      ReferencesXia, Y.F., et al. 2004. J. Immunol. 173, 4207.
      Chen, J.H., et al. 2004. Biochem. Pharmacol. 67, 1337.
      Yu, B.C., et al. 2003. Planta Med. 69, 1075.
      Product Information
      CAS number5508-58-7
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₂₀H₃₀O₅
      Chemical formulaC₂₀H₃₀O₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetNF-κB and AP-1 activation
      Primary Target IC<sub>50</sub>≤ 15 µM against NF-κB and AP-1 activation
      Purity≥95% by TLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSLU3490750
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      产品目录编号 GTIN
      172060-50MGCN 04055977222883