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28745 Sigma-AldrichAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem

This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Dibutyryl-cAMP, Na

Primary Target: PKA

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
16980-89-5	C₁₈H₂₃N₅O₈P · Na

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
28745-100MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	100 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
28745-25MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	25 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
Catalogue Number	28745
Brand Family	Calbiochem®
Synonyms	Dibutyryl-cAMP, Na

References
References	Noveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180. Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108. Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265. Miller, C., et al. 1994. J. Neurosci. Res. 38, 56. Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126. Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174. Park, E.A., et al. 1993. J. Biol. Chem. 268, 613. Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233. Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.

References

Noveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180.
Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108.
Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265.
Miller, C., et al. 1994. J. Neurosci. Res. 38, 56.
Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126.
Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174.
Park, E.A., et al. 1993. J. Biol. Chem. 268, 613.
Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233.
Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.

Product Information
CAS number	16980-89-5
ATP Competitive	N
Form	White lyophilized solid
Hill Formula	C₁₈H₂₃N₅O₈P · Na
Chemical formula	C₁₈H₂₃N₅O₈P · Na
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ200

Applications

Biological Information
Primary Target	PKA
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	ES5055500

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Aqueous stock solutions are stable for up to 3 days at 4°C or for up to 3 months at -20°C. Avoid pH >8.5.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
28745-100MGCN	04055977197839
28745-25MGCN	04055977090970

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem 分析证书

标题	批号
28745	输入批号

参考

参考信息概述
Noveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180. Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108. Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265. Miller, C., et al. 1994. J. Neurosci. Res. 38, 56. Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126. Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174. Park, E.A., et al. 1993. J. Biol. Chem. 268, 613. Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233. Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.

参考信息概述

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	11-March-2008 JSW
Synonyms	Dibutyryl-cAMP, Na
Description	Cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Known to cause an increase in the steady state level of the parathyroid hormone related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
Form	White lyophilized solid
CAS number	16980-89-5
RTECS	ES5055500
Chemical formula	C₁₈H₂₃N₅O₈P · Na
Structure formula
Purity	≥95% by HPLC
Solubility	H₂O (1 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Aqueous stock solutions are stable for up to 3 days at 4°C or for up to 3 months at -20°C. Avoid pH >8.5.
Toxicity	Standard Handling
References	Noveen, A., et al. 1996. Biochem. Biophys. Res. Commun. 219, 180. Tsai, C.H., et al. 1995. J. Cell. Physiol. 164, 108. Leszczynski, D., et al. 1994. Am. J. Pathol. 145, 1265. Miller, C., et al. 1994. J. Neurosci. Res. 38, 56. Hinko, A., and Soloff, M.S. 1993. Endocrinology 132, 126. Ikeda, K., et al. 1993. J. Biol. Chem. 268, 1174. Park, E.A., et al. 1993. J. Biol. Chem. 268, 613. Hei, Y-J., et al. 1991. Mol. Pharmacol. 39, 233. Posternak, T., and Weimann, G. 1974. Methods Enzymol. 38, 399.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Activators > Kinases Activators > Protein Kinase A Activators

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28745 Sigma-AldrichAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem

This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.

同义词: Dibutyryl-cAMP, Na

Recommended Products

概述

重要规格表

价格及供货情况

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem MSDS

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem 分析证书

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This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.

同义词: Dibutyryl-cAMP, Na

Recommended Products

重要规格表

价格及供货情况

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem MSDS

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem 分析证书

参考

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最近查看的内容

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem MSDS

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O^2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem 分析证书