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116802 Sigma-AldrichAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

分析证书
参考
Data Sheet

同义词: 6-Bnz-cAMP, Na

Primary Target: PKA

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
30275-80-0	C₁₇H₁₅N₅O₇P · Na

价格及供货情况

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Description
Overview	A potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
Overview	Note: 10 µmol = 4.55 mg.
Catalogue Number	116802
Brand Family	Calbiochem®
Synonyms	6-Bnz-cAMP, Na

References
References	Døskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249. Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555. Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.

Product Information
CAS number	30275-80-0
ATP Competitive	N
Form	Lyophilized
Hill Formula	C₁₇H₁₅N₅O₇P · Na
Chemical formula	C₁₇H₁₅N₅O₇P · Na
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications
Application	Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.

Biological Information
Primary Target	PKA
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
116802-10UMOLCN	04055977208207

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem 分析证书

标题	批号
116802	输入批号

参考

参考信息概述
Døskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249. Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555. Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	06-September-2007 RFH
Synonyms	6-Bnz-cAMP, Na
Description	A potent, non-degradable, cell-permeable analog of cAMP that binds to the cAMP binding site 2 on the protein kinase A (PKA) regulatory subunit and activates both type I and II PKA. λ_max = 279 nm (H₂O, pH 7.0); ε_max = 17,000 M^-1cm^-1.
Form	Lyophilized
CAS number	30275-80-0
Chemical formula	C₁₇H₁₅N₅O₇P · Na
Structure formula
Purity	≥98% by HPLC
Solubility	H₂O (10 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Døskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249. Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555. Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Activators > Kinases Activators > Protein Kinase A Activators

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