Millipore Sigma Vibrant Logo

658550 AG 1295 - CAS 71897-07-9 - Calbiochem

概述

Replacement Information

重要规格表

CAS #Empirical Formula
71897-07-9C₁₆H₁₄N₂

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
658550-5MGCN
正在查询供货情况......
目前缺货
目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余:另行通知
      其余:另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      塑胶安瓿;塑胶针药瓶 5 mg
      正在检索价格......
      无法检索价格。
      最小订购数量为倍数
      Maximum Quantity is
      以订单确认为准 更多信息
      您节约了 ()。
       
      Request Pricing
      Description
      OverviewA cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss/3T3 cells. Has no effect on EGF receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis. A potent blocker of smooth muscle cell proliferation.
      Catalogue Number658550
      Brand Family Calbiochem®
      Synonyms6,7-Dimethyl-2-phenylquinoxaline
      References
      ReferencesBanai, S., et al. 1998. Circulation 97, 1960.
      Levitzki, A., and Gazit, A. 1995. Science 267, 1782.
      Kovalenko, M., et al. 1994. Cancer Res. 54, 6106.
      Product Information
      CAS number71897-07-9
      ATP CompetitiveY
      FormWhite to yellow solid
      Hill FormulaC₁₆H₁₄N₂
      Chemical formulaC₁₆H₁₄N₂
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPDGFR kinase
      Primary Target IC<sub>50</sub>500 nM against PDGFR kinase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      658550-5MGCN 07790788052225

      Documentation

      AG 1295 - CAS 71897-07-9 - Calbiochem MSDS

      职位

      物料安全数据表 (MSDS) 

      AG 1295 - CAS 71897-07-9 - Calbiochem 分析证书

      标题批号
      658550

      参考

      参考信息概述
      Banai, S., et al. 1998. Circulation 97, 1960.
      Levitzki, A., and Gazit, A. 1995. Science 267, 1782.
      Kovalenko, M., et al. 1994. Cancer Res. 54, 6106.
      数据表

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-September-2020 JSW
      Synonyms6,7-Dimethyl-2-phenylquinoxaline
      DescriptionSelectively inhibits platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and the PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss 3T3 cells. Has no effect on epidermal growth factor (EGF) receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis.
      FormWhite to yellow solid
      CAS number71897-07-9
      Chemical formulaC₁₆H₁₄N₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml) or CH₂Cl₂
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesBanai, S., et al. 1998. Circulation 97, 1960.
      Levitzki, A., and Gazit, A. 1995. Science 267, 1782.
      Kovalenko, M., et al. 1994. Cancer Res. 54, 6106.