Millipore Sigma Vibrant Logo

101500 AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem

概述

Replacement Information

重要规格表

CAS #Empirical Formula
30827-99-7C₈H₁₀FNO₂S · HCl

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
101500-100MGCN
正在查询供货情况......
目前缺货
目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余:另行通知
      其余:另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      玻璃瓶 100 mg
      正在检索价格......
      无法检索价格。
      最小订购数量为倍数
      Maximum Quantity is
      以订单确认为准 更多信息
      您节约了 ()。
       
      Request Pricing
      101500-1GMCN
      正在查询供货情况......
      目前缺货
目前缺货
      有货 
      停产
      少量现货
      供货情况有待确认
        其余:另行通知
          其余:另行通知
          另行通知
          联系客户服务
          Contact Customer Service

          玻璃瓶 1 gm
          正在检索价格......
          无法检索价格。
          最小订购数量为倍数
          Maximum Quantity is
          以订单确认为准 更多信息
          您节约了 ()。
           
          Request Pricing
          101500-500MGCN
          正在查询供货情况......
          目前缺货
目前缺货
          有货 
          停产
          少量现货
          供货情况有待确认
            其余:另行通知
              其余:另行通知
              另行通知
              联系客户服务
              Contact Customer Service

              塑胶安瓿;塑胶针药瓶 500 mg
              正在检索价格......
              无法检索价格。
              最小订购数量为倍数
              Maximum Quantity is
              以订单确认为准 更多信息
              您节约了 ()。
               
              Request Pricing
              101500-50MGCN
              正在查询供货情况......
              目前缺货
目前缺货
              有货 
              停产
              少量现货
              供货情况有待确认
                其余:另行通知
                  其余:另行通知
                  另行通知
                  联系客户服务
                  Contact Customer Service

                  玻璃瓶 50 mg
                  正在检索价格......
                  无法检索价格。
                  最小订购数量为倍数
                  Maximum Quantity is
                  以订单确认为准 更多信息
                  您节约了 ()。
                   
                  Request Pricing
                  Description
                  OverviewSpecific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications. Also available as a 50 mM solution in H2O (Cat. No. 508436).
                  Catalogue Number101500
                  Brand Family Calbiochem®
                  Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl
                  Application Data
                  References
                  ReferencesCitron, M., et al. 1996. Neuron 17, 171.
                  Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
                  Mintz, G.R. 1993. BioPharm. 6, 34.
                  Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
                  Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
                  Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
                  Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
                  Product Information
                  CAS number30827-99-7
                  ATP CompetitiveN
                  FormWhite to off-white solid
                  Hill FormulaC₈H₁₀FNO₂S · HCl
                  Chemical formulaC₈H₁₀FNO₂S · HCl
                  ReversibleN
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ100
                  Applications
                  Biological Information
                  Primary Targetchymotrypsin
                  Purity>97% by HPLC
                  Physicochemical Information
                  Cell permeableN
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Toxicity Standard Handling
                  Storage -20°C
                  Protect from Moisture Protect from moisture
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 2 months at 4°C. Slight hydrolysis occurs at alkaline pH (8-9).
                  Packaging Information
                  Packaged under inert gas Packaged under inert gas
                  Transport Information
                  Supplemental Information
                  Specifications
                  Global Trade Item Number
                  产品目录编号 GTIN
                  101500-100MGCN 04055977226317
                  101500-1GMCN 04055977226300
                  101500-500MGCN 04055977226348
                  101500-50MGCN 04055977226331

                  Documentation

                  AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem MSDS

                  职位

                  物料安全数据表 (MSDS) 

                  AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem 分析证书

                  标题批号
                  101500

                  参考

                  参考信息概述
                  Citron, M., et al. 1996. Neuron 17, 171.
                  Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
                  Mintz, G.R. 1993. BioPharm. 6, 34.
                  Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
                  Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
                  Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
                  Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.

                  小册子

                  标题
                  Bulk Product Guide

                  引用

                  标题
                • Catherine Mee-Hie Cho, Ashok Mulchandani and Wilfred Chen. (2006) Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides. Protein Engineering Design and Selection 19, 99-105.
                • Ok Hee Ryu, et al. (2005) Proteolysis of MIP-1α isoforms LD78β and LD78α by neutrophil-derived serine proteases. Journal of Biological Chemistry 280, 17415-17421.
                • Sharon Yagur-Kroll and Orna Amster-Choder. (2005) Dynamic membrane topology of the E. coli -glucoside transporter β-glucosidase transporter BglF. Journal of Biological Chemistry 280, 19306-19318.
                • Valerie A. Fadok, et al. (2001) Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases. Journal of Immunology 166, 6847-6854.
                • 数据表

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision27-September-2013 JSW
                  Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl
                  Application Data
                  DescriptionSpecific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K.
                  FormWhite to off-white solid
                  Intert gas (Yes/No) Packaged under inert gas
                  CAS number30827-99-7
                  Chemical formulaC₈H₁₀FNO₂S · HCl
                  Structure formulaStructure formula
                  Purity>97% by HPLC
                  SolubilityH₂O (25 mg/ml)
                  Storage Protect from moisture
                  -20°C
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 2 months at 4°C. Slight hydrolysis occurs at alkaline pH (8-9).
                  Toxicity Standard Handling
                  ReferencesCitron, M., et al. 1996. Neuron 17, 171.
                  Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
                  Mintz, G.R. 1993. BioPharm. 6, 34.
                  Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
                  Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
                  Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
                  Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
                  Citation
                • Catherine Mee-Hie Cho, Ashok Mulchandani and Wilfred Chen. (2006) Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides. Protein Engineering Design and Selection 19, 99-105.
                • Ok Hee Ryu, et al. (2005) Proteolysis of MIP-1α isoforms LD78β and LD78α by neutrophil-derived serine proteases. Journal of Biological Chemistry 280, 17415-17421.
                • Sharon Yagur-Kroll and Orna Amster-Choder. (2005) Dynamic membrane topology of the E. coli -glucoside transporter β-glucosidase transporter BglF. Journal of Biological Chemistry 280, 19306-19318.
                • Valerie A. Fadok, et al. (2001) Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases. Journal of Immunology 166, 6847-6854.
                • 相关产品和应用

                  Related Products

                  产品目录编号 描述  
                  199001 Benzamidine, Hydrochloride - CAS 1670-14-0 - Calbiochem 显示价格及库存情况
                  524625 Phosphatase Inhibitor Cocktail Set II 显示价格及库存情况
                  539132 Protease Inhibitor Cocktail Set II - Calbiochem 显示价格及库存情况
                  539134 Protease Inhibitor Cocktail Set III, EDTA-Free - Calbiochem 显示价格及库存情况

                  种类

                  Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors