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A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Used in blocking general excitatory synaptic transmissions.
Tong, G., et al. 1994. Neuron13, 1195. Leach, J., et al. 1986. Eur. J. Pharmacol.121, 173. Watkins, C., et al. 1981. Annu. Rev. Pharmacol. Toxicol.21, 165.
数据表
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A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Used in blocking general excitatory synaptic transmissions.
Form
White solid
CAS number
46026-75-9
Chemical formula
C₇H₁₁NO₄
Structure formula
Purity
≥98% by HPLC
Solubility
H₂O (100 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Tong, G., et al. 1994. Neuron13, 1195. Leach, J., et al. 1986. Eur. J. Pharmacol.121, 173. Watkins, C., et al. 1981. Annu. Rev. Pharmacol. Toxicol.21, 165.
