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203984 Sigma-Aldrich2,3-Butanedione 2-Monoxime - CAS 57-71-6 - Calbiochem

An inhibitor of skeletal and cardiac muscle contraction.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: BDM

Primary Target: Ca²⁺ currents in adult rat cervical ganglion in a reversible and dose-dependent manner

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
57-71-6	C₄H₇NO₂

价格及供货情况

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Description
Overview	An inhibitor of skeletal and cardiac muscle contraction. A general reversible inhibitor of myosin ATPase in eukaryotes. A “chemical phosphatase,” which dephosphorylates acetylcholinesterase poisoned with organophosphates. Inhibits Ca²⁺ currents in adult rat cervical ganglion in a reversible and dose-dependent manner (IC₅₀ = 18.3 nM). Also shown to induce Ca²⁺ release from canine cardiac sarcoplasmic reticulum (SR).
Catalogue Number	203984
Brand Family	Calbiochem®
Synonyms	BDM

References
References	Phillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun. 229, 154. Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol. 74, 305. Zhu, Y., and Ikeda, S.R. 1993. Neurosci. Lett. 155, 24.

Product Information
CAS number	57-71-6
ATP Competitive	N
Form	White to off-white solid
Hill Formula	C₄H₇NO₂
Chemical formula	C₄H₇NO₂
Hygroscopic	Hygroscopic
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Ca²⁺ currents in adult rat cervical ganglion in a reversible and dose-dependent manner
Primary Target IC<sub>50</sub>	18.3 nM inhibiting Ca2+ currents in adult rat cervical ganglion in a reversible and dose-dependent manner
Purity	≥98% by GC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	EK3150000

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
203984-500MGCN	04055977219951

Documentation

2,3-Butanedione 2-Monoxime - CAS 57-71-6 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

2,3-Butanedione 2-Monoxime - CAS 57-71-6 - Calbiochem 分析证书

标题	批号
203984	输入批号

参考

参考信息概述
Phillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun. 229, 154. Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol. 74, 305. Zhu, Y., and Ikeda, S.R. 1993. Neurosci. Lett. 155, 24.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	04-October-2017 JSW
Synonyms	BDM
Description	An inhibitor of skeletal and cardiac muscle contraction. A "chemical phosphatase" that dephosphorylates acetylcholinesterase poisoned with organophosphates. Inhibits Ca²⁺ currents in adult rat cervical ganglion in a reversible and dose-dependent manner (IC₅₀ = 18.3 nM). Also shown to induce Ca²⁺ release from canine cardiac sarcoplasmic reticulum (SR).
Form	White to off-white solid
CAS number	57-71-6
RTECS	EK3150000
Chemical formula	C₄H₇NO₂
Structure formula
Purity	≥98% by GC
Solubility	Methanol (100 mg/ml)
Storage	+2°C to +8°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Phillips, R.M., and Altschuld, R.A. 1996. Biochem. Biophys. Res. Commun. 229, 154. Sellin, L.C., and McArdle, J.J. 1994. Pharmacol. Toxicol. 74, 305. Zhu, Y., and Ikeda, S.R. 1993. Neurosci. Lett. 155, 24.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > ATPase/GTPase Inhibitors > ATPase Inhibitors

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