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Native β2-microglobulin from human urine. A useful marker for the determination of AIDS progression in HIV-infected subjects. Increased levels may also indicate increased proliferation of tumor masses.
Catalogue Number
475823
Brand Family
Calbiochem®
Synonyms
β₂M
References
References
Zabay, J.M., et al. 1995. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 8, 266. Mady, B.J., et al. 1991. J. Immunol.147, 3139. Lampson, L.A. 1990. J. Immunol. 144, 512. Calzia, R., et al. 1989. Adv. Exp. Med. Biol.257, 225. Ninomiya, Y., and Arakawa, M. 1989. Diabetes Res.10, 129.
Product Information
Form
Liquid
Formulation
In PBS, 150 mM NaCl, 20 mM phosphate buffer, pH 7.3.
Zabay, J.M., et al. 1995. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 8, 266. Mady, B.J., et al. 1991. J. Immunol.147, 3139. Lampson, L.A. 1990. J. Immunol. 144, 512. Calzia, R., et al. 1989. Adv. Exp. Med. Biol.257, 225. Ninomiya, Y., and Arakawa, M. 1989. Diabetes Res.10, 129.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
08-August-2008 RFH
Synonyms
β₂M
Description
Native β2-microglobulin from human urine. Single chain polypeptide that is the constant component of Class I MHC, which is located on most nucleated cells. It is also a normal constituent of serum and urine. Increased levels of this protein in the serum are used as a marker for impairments of renal function and a variety of lymphoproliferative diseases.
Form
Liquid
Formulation
In PBS, 150 mM NaCl, 20 mM phosphate buffer, pH 7.3.
Source
Prepared from urine that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity
≥98% by SDS-PAGE
Storage
Avoid freeze/thaw
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, product can be stored at 4°C for up to 6 months.
Toxicity
Standard Handling
References
Zabay, J.M., et al. 1995. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 8, 266. Mady, B.J., et al. 1991. J. Immunol.147, 3139. Lampson, L.A. 1990. J. Immunol. 144, 512. Calzia, R., et al. 1989. Adv. Exp. Med. Biol.257, 225. Ninomiya, Y., and Arakawa, M. 1989. Diabetes Res.10, 129.
