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Recombinant, human β2-microglobulin fused at the N-terminus to a His•Tag® sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag® sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.
Catalogue Number
475828
Brand Family
Calbiochem®
Synonyms
rhβ₂M
References
References
Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613. Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.
β₂-Microglobulin, Human, Recombinant, E. coli 分析证书
标题
批号
475828
参考
参考信息概述
Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613. Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
13-October-2010 JSW
Synonyms
rhβ₂M
Description
Recombinant, human β2-microglobulin fused at the N-terminus to a His•Tag® sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag® sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.
Form
Lyophilized
Purity
single band by SDS-PAGE
Solubility
Aqueous buffers
Storage
Avoid freeze/thaw
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C).
Toxicity
Standard Handling
References
Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613. Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.