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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

454180 Sigma-Aldrich2-Methoxyestradiol - CAS 362-07-2 - Calbiochem

A natural metabolite of 17β-estradiol that is devoid of estrogenic activity.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene

Primary Target: Inhibits cell proliferation and angiogenesis

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
362-07-2	C₁₉H₂₆O₃

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
454180-10MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	铝滚桶	10 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
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Description
Overview	A natural metabolite of 17β-estradiol that is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Markedly inhibits the neovascularization of solid tumors and suppresses tumor growth in mice. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function.
Catalogue Number	454180
Brand Family	Calbiochem®
Synonyms	2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene

References
References	Aizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863. Cushman, M., et al. 1995. J. Med. Chem. 38, 2041. D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964. Forsis, T., et al. 1994. Nature 368, 237.

Product Information
CAS number	362-07-2
ATP Competitive	N
Form	White crystalline solid
Hill Formula	C₁₉H₂₆O₃
Chemical formula	C₁₉H₂₆O₃
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Inhibits cell proliferation and angiogenesis
Purity	≥90% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 23/24/25-36/37/38 Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.
S Phrase	S: 22-26-36/37/39-45 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Toxic
Hazardous Materials Attention:	Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage	+15°C to +30°C
Do not freeze	Ok to freeze

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
454180-10MGCN	04055977204728
454180-50MGCN	04055977204735

Documentation

2-Methoxyestradiol - CAS 362-07-2 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

2-Methoxyestradiol - CAS 362-07-2 - Calbiochem 分析证书

标题	批号
454180	输入批号

参考

参考信息概述
Aizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863. Cushman, M., et al. 1995. J. Med. Chem. 38, 2041. D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964. Forsis, T., et al. 1994. Nature 368, 237.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	15-May-2008 RFH
Synonyms	2-Methoxy-3,17β-dihydroxyestra-1,3,5(10)-triene
Description	A natural metabolite of 17β-estradiol that is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Markedly inhibits neovascularization of solid tumors and suppresses tumor growth in mice. Binds to the colchicine binding site of tubulin and has been suggested to function as a natural regulator of microtubule assembly and function.
Form	White crystalline solid
CAS number	362-07-2
Chemical formula	C₁₉H₂₆O₃
Structure formula
Purity	≥90% by HPLC
Solubility	DMSO or Ethanol
Storage	+15°C to +30°C
Do Not Freeze	Ok to freeze
Toxicity	Toxic
References	Aizu-Yokata, E., et al. 1995. Cancer Res. 55, 1863. Cushman, M., et al. 1995. J. Med. Chem. 38, 2041. D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3964. Forsis, T., et al. 1994. Nature 368, 237.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Angiogenesis Inhibitors > Angiogenesis Inhibitors

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