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565761 γ-Secretase Inhibitor IV - Calbiochem

概述

重要规格表

Empirical Formula
C₂₅H₂₆N₂O₃

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
565761-1MGCN
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      Description
      OverviewA cell-permeable, reversible inhibitor of γ-secretase. Equipotently inhibits the release of Aβx-40 (ED50 = 2.6 µM) and Aβx-42 (ED50 = 2.7 µM) in HEK293 cells stably transfected with the Amyloid Precursor Protein Swedish mutants.
      Catalogue Number565761
      Brand Family Calbiochem®
      Synonyms2-Naphthoyl-VF-CHO, N-(2-Naphthoyl)-Val-phenylalaninal
      References
      ReferencesGreen, K.N., et al. 2002. J. Physiol. 541.3, 1013.
      Sinha, S. and Lieberburg, I. 1999. Proc. Natl. Acad. Sci. USA 96, 11049.
      Product Information
      ATP CompetitiveN
      FormWhite lyophilized solid
      Hill FormulaC₂₅H₂₆N₂O₃
      Chemical formulaC₂₅H₂₆N₂O₃
      ReversibleY
      Quality LevelMQ100
      Biological Information
      Primary Targetx-40
      Primary Target IC<sub>50</sub>ED50 = 2.6 µM for Aβx-40
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide Sequence2-Naphthoyl-Val-Phe-CHO
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      产品目录编号 GTIN
      565761-1MGCN 04055977267716