数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

487910 Sigma-Aldrich(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem

Nitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet
Citations

同义词: SNAP

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
79032-48-7	C₇H₁₂N₂O₄S

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
487910-1SETCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	玻璃瓶	1 set	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
487910-20MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	20 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	Nitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM). Markedly activates soluble guanylate cyclase. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Catalogue Number	487910
Brand Family	Calbiochem®
Synonyms	SNAP

References
References	Nishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163. Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1. Fehsel, K., et al. 1995. J. Immunol. 155, 2858. Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180. Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107. Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.

Product Information
CAS number	79032-48-7
ATP Competitive	N
Form	Pale green solid
Hill Formula	C₇H₁₂N₂O₄S
Chemical formula	C₇H₁₂N₂O₄S
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Nitric oxide donor
Primary Target IC<sub>50</sub>	EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	SNAP evolves NO immediately upon solubilization; reconstitute just prior to use.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
487910-1SETCN	04055977200324
487910-20MGCN	04055977200331

Documentation

(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem 分析证书

标题	批号
487910	输入批号

参考

参考信息概述
Nishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163. Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1. Fehsel, K., et al. 1995. J. Immunol. 155, 2858. Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180. Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107. Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure

引用

标题

Bysani Chandrasekar, et al. (2005) The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-J. Journal of Biological Chemistry 280, 26263-26277.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	25-October-2016 JSW
Synonyms	SNAP
Description	Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t_1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Form	Pale green solid
CAS number	79032-48-7
Chemical formula	C₇H₁₂N₂O₄S
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (25 mg/ml), Ethanol (25 mg/ml), or Methanol
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	SNAP evolves NO immediately upon solubilization; reconstitute just prior to use.
Toxicity	Irritant
References	Nishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163. Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1. Fehsel, K., et al. 1995. J. Immunol. 155, 2858. Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180. Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107. Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.
Citation	Bysani Chandrasekar, et al. (2005) The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-J. Journal of Biological Chemistry 280, 26263-26277.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Nucleotides, Nucleosides, Purines, Pyrimidines and Nucleic Acids > Nitric Oxide Donors/Precursors

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