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Recombinant, mouse γ-interferon, consisting of 134 amino acids, expressed in E. coli as a single, non-glycosylated polypeptide. A multi-functional protein exhibiting antiviral and antitumor properties. Regulates the development of specific immune responses. Protects against bacterial sepsis in murine models.
Note: 1 KU = 1000 units.
Catalogue Number
407303
Brand Family
Calbiochem®
References
References
Zantl, N., et al. 1998. Infect. Immun. 66, 2300. Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
Zantl, N., et al. 1998. Infect. Immun. 66, 2300. Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
08-June-2011 JSW
Description
Recombinant, mouse γ-interferon, consisting of 134 amino acids, expressed in E. coli as a single, non-glycosylated polypeptide. A multi-functional protein exhibiting antiviral and antitumor properties. Regulates the development of specific immune responses. Protects against bacterial sepsis in murine models.
Form
Liquid
Formulation
In 10 mM PBS, pH 7.4.
Purity
≥95% by SDS-PAGE
Biological activity
< 0.1 ng/ml (< 1 x 10⁷ U/mg) as determined by cytopathic affect inhibition assay using murine NIH 3T3 cells treated with EMC virus.
Solubility
Dilute only in buffers containing protein such as 0.1% BSA.
Storage
Avoid freeze/thaw
≤ -70°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-70°C).
Toxicity
Standard Handling
Merck USA index
14, 4992
References
Zantl, N., et al. 1998. Infect. Immun. 66, 2300. Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
