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GF311 RANTES Protein, Human Recombinant Animal Free

GF311
20 µg  
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      Overview

      Key Spec Table

      SourcePurity
      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF311
      DescriptionRANTES Protein, Human Recombinant Animal Free
      Alternate Names
      • CCL5
      • EoCP
      • Eosinophil chemotactic cytokine
      • SIS-delta
      • Small-inducible cytokine A5
      • T cell-specific protein P228
      Background InformationRANTES , also known as CCL5, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
      Product Information
      Formulation
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ300
      Applications
      ApplicationThe RANTES protein, also known as CCL5 protein, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract & activate leukocytes. Manufactured using all non-animal reagents.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityNone
      Entrez Gene Number
      UniProt Number
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size20 µg
      Global Trade Item Number
      Catalogue Number GTIN
      GF311 04053252691478