540500 Sigma-AldrichPurvalanol A - CAS 212844-53-6 - Calbiochem
A potent, cell-permeable, reversible, and selective inhibitor of cyclin-dependent kinases.
More>> A potent, cell-permeable, reversible, and selective inhibitor of cyclin-dependent kinases. Less<<Synonyms: 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropyl-purine
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Overview
Replacement Information |
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Key Spec Table
CAS # | Empirical Formula |
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212844-53-6 | C₁₉H₂₅ClN₆O |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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540500-1MGCN |
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Plastic ampoule | 1 mg |
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References | |
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References | Gray, N.S., et al. 1998. Science 281, 533. |
Product Information | |
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CAS number | 212844-53-6 |
ATP Competitive | N |
Declaration | Sold under license of U.S. Patents 6,617,331 and 6,803,371. |
Form | Off-white solid |
Hill Formula | C₁₉H₂₅ClN₆O |
Chemical formula | C₁₉H₂₅ClN₆O |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | Cdc2/cyclin B |
Primary Target IC<sub>50</sub> | 4 nM for Cdc2/cyclin B; 70 nM for Cdk2/cyclin A; 35 nM for Cdk2/cyclin E; 75 nM for Cdk5/p35 |
Purity | ≥97% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Transport Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
540500-1MGCN | 04055977268812 |
Documentation
Purvalanol A - CAS 212844-53-6 - Calbiochem SDS
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Purvalanol A - CAS 212844-53-6 - Calbiochem Certificates of Analysis
Title | Lot Number |
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540500 |
References
Reference overview |
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Gray, N.S., et al. 1998. Science 281, 533. |