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538904 Prostaglandin E₂ - CAS 363-24-6 - Calbiochem

Prostaglandin E₂, CAS 363-24-6, is a product of arachidonic acid metabolism that binds to EP1, EP2, EP3, & EP4 receptors with high affinity (Kd = 1-10 nM). Involved in vasodilator actions of kinins.

Prostaglandin E₂ - CAS 363-24-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PGE₂

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538904
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
363-24-6C₂₀H₃₂O₅

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      Description
      OverviewInvolved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
      Catalogue Number538904
      Brand Family Calbiochem®
      SynonymsPGE₂
      References
      ReferencesLi, X., et al. 1995. Am. J. Physiol. 269, C986.
      Kessler, W., et al. 1992. Exp. Brain Res. 91, 467.
      Product Information
      CAS number363-24-6
      ATP CompetitiveN
      FormWhite to light yellow solid
      Hill FormulaC₂₀H₃₂O₅
      Chemical formulaC₂₀H₃₂O₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationProstaglandin E₂, CAS 363-24-6, is a product of arachidonic acid metabolism that binds to EP1, EP2, EP3, & EP4 receptors with high affinity (Kd = 1-10 nM). Involved in vasodilator actions of kinins.
      Biological Information
      Primary TargetInvolved in vasodilator actions of kinins such as bradykinin
      Primary Target IC<sub>50</sub>25-50 µM inhibiting MAP kinase in rat mesangial cells
      Purity>98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUK8000000
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Harmful
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      538904-1MGCN 07790788051266

      Documentation

      Prostaglandin E₂ - CAS 363-24-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Prostaglandin E₂ - CAS 363-24-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      538904

      References

      Reference overview
      Li, X., et al. 1995. Am. J. Physiol. 269, C986.
      Kessler, W., et al. 1992. Exp. Brain Res. 91, 467.

      Brochure

      Title
      Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-June-2013 JSW
      SynonymsPGE₂
      DescriptionInvolved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
      FormWhite to light yellow solid
      CAS number363-24-6
      RTECSUK8000000
      Chemical formulaC₂₀H₃₂O₅
      Structure formulaStructure formula
      Purity>98% by HPLC
      SolubilityAcetone, ethanol, methanol, or ethyl acetate
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Harmful
      Merck USA index14, 7877
      ReferencesLi, X., et al. 1995. Am. J. Physiol. 269, C986.
      Kessler, W., et al. 1992. Exp. Brain Res. 91, 467.