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480001 NDSB-195 - CAS 160255-06-1 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.

NDSB-195 - CAS 160255-06-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dimethylethylammonium Propane Sulfonate

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480001
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
160255-06-1C₇H₁₇NO₃S

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480001-25GMCN
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      Description
      OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Easily removed by dialysis.
      Catalogue Number480001
      Brand Family Calbiochem®
      SynonymsDimethylethylammonium Propane Sulfonate
      References
      ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
      Vuillard, L., et al. 1995. Biochem. J. 305, 337.
      Vuillard, L., et al. 1994. FEBS Lett. 353, 294.
      Product Information
      CAS number160255-06-1
      FormWhite solid
      Hill FormulaC₇H₁₇NO₃S
      Chemical formulaC₇H₁₇NO₃S
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      480001-25GMCN 04055977201758

      Documentation

      NDSB-195 - CAS 160255-06-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      NDSB-195 - CAS 160255-06-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      480001

      References

      Reference overview
      Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
      Vuillard, L., et al. 1995. Biochem. J. 305, 337.
      Vuillard, L., et al. 1994. FEBS Lett. 353, 294.

      Brochure

      Title
      Biological Detergents Brochure
      Bulk Product Guide
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      SynonymsDimethylethylammonium Propane Sulfonate
      DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
      FormWhite solid
      CAS number160255-06-1
      Chemical formulaC₇H₁₇NO₃S
      Structure formulaStructure formula
      Purity≥95% by TLC
      SolubilityH₂O
      Storage +15°C to +30°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Toxicity Irritant
      ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
      Vuillard, L., et al. 1995. Biochem. J. 305, 337.
      Vuillard, L., et al. 1994. FEBS Lett. 353, 294.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Detergents > Non-Detergent Sulfobetaines