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106756 Methyl 4-hydroxybenzoate sodium salt

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
5026-62-0225-714-1C₈H₇NaO₃Na⁺[4-(O)C₆H₄(COOCH₃)]⁻174.13 g/molPh Eur,BP,NF

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      Description
      Catalogue Number106756
      Synonyms4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt
      DescriptionMethyl 4-hydroxybenzoate sodium salt
      References
      Product Information
      CAS number5026-62-0
      EC number225-714-1
      GradePh Eur,BP,NF
      Hill FormulaC₈H₇NaO₃
      Chemical formulaNa⁺[4-(O)C₆H₄(COOCH₃)]⁻
      Molar Mass174.13 g/mol
      HS Code2918 29 22
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.42 g/cm3 (20 °C)
      Ignition temperature>600 °C
      Melting Point>125 °C
      pH value9.7 - 10.3 (1 g/l, H₂O)
      Bulk density700 kg/m3
      Solubility333 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat > 5000 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Statement(s)H315: Causes skin irritation.
      H318: Causes serious eye damage.
      H412: Harmful to aquatic life with long lasting effects.
      Precautionary Statement(s)P264: Wash skin thoroughly after handling.
      P273: Avoid release to the environment.
      P280: Wear protective gloves/ eye protection/ face protection.
      P302 + P352: IF ON SKIN: Wash with plenty of water.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      P332 + P313: If skin irritation occurs: Get medical advice/ attention.
      Signal WordDanger
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Categories of dangerirritant
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDKein Gefahrgut
      Declaration (transport by air) IATA-DGRNo Dangerous Good
      Declaration (transport by sea) IMDG-CodeNo Dangerous Good
      Supplemental Information
      Specifications
      Assay (HPLC, calc. on anhydrous substance, Ph.Eur.)95.0 - 102.0 %
      Assay (HPLC, calc. on anhydrous substance, NF)95.0 - 102.0 %
      Identity (IR-spectrum)passes test
      Identity (wet chemistry)passes test
      Appearance of solution (100 g/l, CO₂-free water)clear and not more intense in color than reference solution BY₆
      Solubilitypasses test
      pH-value (1 g/l in CO₂-free Water)9.5 - 10.5
      Chloride (Cl)≤ 350 ppm
      Sulfate (SO₄)≤ 300 ppm
      Related substances (HPLC, Ph. Eur.)passes test
      4-Hydroxy benzoic acid (Ph. Eur.)≤ 3.0 %
      Sum of all impurities (without 4-Hydroxybenzoic acid (Ph.Eur.))≤ 1.0 %
      Largest unspecified impurity (Ph.Eur.)≤ 0.5 %
      Related substances (HPLC, NF)passes test
      4-Hydroxy benzoic acid (NF)≤ 3.0 %
      Sum of all impurities (without 4-Hydroxybenzoic acid (NF))≤ 1.0 %
      Largest unspecified impurity (NF)≤ 0.5 %
      Methanol (HS-GC)≤ 3000 ppm
      Other residual solvents (ICH Q3C)excluded by manufactoring process
      Water (according to Karl Fischer)≤ 5.0 %
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds Ph Eur, BP,NF
      Global Trade Item Number
      Catalogue Number GTIN
      1.06756.5000 04022536081809

      Documentation

      Material Qualification Dossier

      TitleVersion
      9.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      Methyl 4-hydroxybenzoate sodium salt SDS

      Title

      Safety Data Sheet (SDS) 

      Methyl 4-hydroxybenzoate sodium salt Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1.06756.5000 Plastic bottlePDF Specification Document

      Certificates

      Title