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106757 Methyl 4-hydroxybenzoate

EMPROVE® EXPERT Ph Eur,BP,ChP,JP,NF

Methyl 4-hydroxybenzoate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Methylparaben, 4-Hydroxybenzoic acid methyl ester

CAS #: 99-76-3 EC Number: 202-785-7 Molar Mass: 152.15 g/mol Chemical Formula: 4-(OH)C₆H₄(COOCH₃) Hill Formula: C₈H₈O₃ Grade: Ph Eur,BP,ChP,JP,NF
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106757
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Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
99-76-3202-785-7C₈H₈O₃4-(OH)C₆H₄(COOCH₃)152.15 g/molPh Eur,BP,ChP,JP,NF

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      Description
      Catalogue Number106757
      SynonymsMethylparaben, 4-Hydroxybenzoic acid methyl ester
      DescriptionMethyl 4-hydroxybenzoate
      References
      Product Information
      CAS number99-76-3
      EC number202-785-7
      GradePh Eur,BP,ChP,JP,NF
      Hill FormulaC₈H₈O₃
      Chemical formula4-(OH)C₆H₄(COOCH₃)
      Molar Mass152.15 g/mol
      HS Code2918 29 22
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.38 g/cm3 (20 °C)
      Flash point168 °C Not applicable
      Ignition temperature>600 °C
      Melting Point125 °C
      pH value5.72 (1.88 g/l, H₂O, 20 °C) (saturated solution)
      Vapor pressure<1 hPa (20 °C)
      Bulk density300 - 400 kg/m3
      Solubility1.88 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 2100 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Statement(s)H411: Toxic to aquatic life with long lasting effects.
      Precautionary Statement(s)P273: Avoid release to the environment.
      P391: Collect spillage.
      P501: Dispose of contents/ container to an approved waste disposal plant.
      RTECSDH2450000
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
      Declaration (transport by air) IATA-DGRUN 3077 , 9, III
      Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
      Supplemental Information
      Specifications
      Assay (HPLC, Ph. Eur., BP, JP, NF)98.0 - 102.0 %
      Assay (HPLC, calc. on dried substance) (ChP)98.0 - 102.0 %
      Identity (IR-spectrum)passes test
      Identity (melting range)passes test
      Identity (HPLC) (ChP)passes test
      Identity (UV-spectrum)passes test
      Appearance of solution (100 g/l, Ethanol 96 %)clear and not more intense in color than reference solution BY₆
      Appearance of solution (100 g/l, ethanol 96 %) (ChP)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₁ or YG₁
      Aciditypasses test
      Melting range (lower value)≥ 125 °C
      Melting range (upper value)≤ 128 °C
      Chloride (Cl)≤ 350 ppm
      Sulfate (SO₄)≤ 240 ppm
      As (Arsenic)≤ 1 ppm
      Heavy metals (as Pb)≤ 10 ppm
      Related substances (HPLC, Ph. Eur., BP, ChP, JP, NF)passes test
      p-Hydroxy benzoic acid≤ 0.3 %
      Largest unspecified impurity≤ 0.4 %
      Sum of all impurities≤ 0.8 %
      Methanol (HS-GC)≤ 3000 ppm
      Other residual solvents (ICH Q3C)excluded by manufactoring process
      Sulfated ash (600 °C)≤ 0.1 %
      Residue on ignition (500 °C)≤ 0.1 %
      Loss on drying (room temperature, vacuum)≤ 0.5 %
      Total aerobic microbial count (TAMC)≤ 10²
      Total combined yeasts/moulds count (TYMC)≤ 10²
      Endotoxins≤ 200 I.U./g
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Not for food use.
      Corresponds to Ph Eur, BP, ChP, JP, NF.
      Global Trade Item Number
      Catalogue Number GTIN
      1.06757.5000 04022536081847

      Documentation

      Material Qualification Dossier

      TitleVersion
      8.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      Methyl 4-hydroxybenzoate SDS

      Title

      Safety Data Sheet (SDS) 

      Methyl 4-hydroxybenzoate Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1.06757.5000 Fibre cartonPDF Specification Document

      Certificates

      Title