565784 Sigma-AldrichInSolution™ γ-Secretase Inhibitor IX - Calbiochem
InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
More>> InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO. Less<<Synonyms: N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester, DAPT
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Overview
Key Spec Table
Empirical Formula |
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C₂₃H₂₆F₂N₂O₄ |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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565784-10MGCN |
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Plastic ampoule | 10 mg |
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565784-5MGCN |
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Glass bottle | 5 mg |
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Description | |
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Catalogue Number | 565784 |
Brand Family | Calbiochem® |
Synonyms | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester, DAPT |
References | |
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References | Oddo, S., et al. 2004. Neuron 43, 321. Dovey, H.F., et al. 2001. J. Neurochem. 76, 173. Vandermeeren, M., et al. 2001. Neurosci. Lett. 315, 145. |
Product Information | |
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ATP Competitive | N |
Form | Clear colorless liquid |
Formulation | A 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of γ-Secretase Inhibitor IX (Cat. No. 565770) in DMSO. |
Hill Formula | C₂₃H₂₆F₂N₂O₄ |
Chemical formula | C₂₃H₂₆F₂N₂O₄ |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | Aβtotal |
Primary Target IC<sub>50</sub> | 115 nM, 200 nM against Aβtotal, Aβ42, respectively |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Catalogue Number | GTIN |
565784-10MGCN | 04055977267303 |
565784-5MGCN | 04055977191806 |