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565784 InSolution™ γ-Secretase Inhibitor IX - Calbiochem

InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester, DAPT

Primary Target: Aβtotal
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565784
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Overview

Key Spec Table

Empirical Formula
C₂₃H₂₆F₂N₂O₄

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565784-10MGCN
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      565784-5MGCN
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          Description
          Catalogue Number565784
          Brand Family Calbiochem®
          SynonymsN-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester, DAPT
          References
          ReferencesOddo, S., et al. 2004. Neuron 43, 321.
          Dovey, H.F., et al. 2001. J. Neurochem. 76, 173.
          Vandermeeren, M., et al. 2001. Neurosci. Lett. 315, 145.
          Product Information
          ATP CompetitiveN
          FormClear colorless liquid
          FormulationA 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of γ-Secretase Inhibitor IX (Cat. No. 565770) in DMSO.
          Hill FormulaC₂₃H₂₆F₂N₂O₄
          Chemical formulaC₂₃H₂₆F₂N₂O₄
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Biological Information
          Primary TargetAβtotal
          Primary Target IC<sub>50</sub>115 nM, 200 nM against Aβtotal, Aβ42, respectively
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Irritant
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and freeze (-20°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Global Trade Item Number
          Catalogue Number GTIN
          565784-10MGCN 04055977267303
          565784-5MGCN 04055977191806