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GF440 HumanKine® TGF beta 2, Human Recombinant Xeno-Free

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P61812
GF440
5 µg  
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      Overview

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      Bulk Size Quantities of HumanKine Growth Factors are Available.
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      Key Spec Table

      SourcePurity
      HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
      Description
      Catalogue NumberGF440
      Trade Name
      • HumanKine®
      DescriptionHumanKine® TGF beta 2, Human Recombinant Xeno-Free
      Alternate Names
      • TGFb2
      • TGFbII
      • TGFB
      • Transforming Growth Factor-β2
      Background InformationTransforming Growth Factor- beta2 (TGFb2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. TGfb2 regulates proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers.
      Product Information
      Formulation
      PresentationProduct is presented in 50mM NaOAc pH 4.5 and filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ300
      Biological Information
      PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
      SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
      UniProt Number
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by the dose dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2). ED50 is typically 0.1-0.5 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
      Packaging Information
      Material Size5 µg
      Global Trade Item Number
      Catalogue Number GTIN
      GF440 04053252906077