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204870 Complement C3d, Human

Complement C3d, Human is a native, 30 kDa polypeptide formed by the limited digestion of iC3b by trypsin or elastin. The binding of C3d to CR2 on B lymphocytes enhances B cell activation.

Complement C3d, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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204870
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Overview

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Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
204870-100UGCN
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      		 Plastic ampoule 100 μg
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      Description
      OverviewNative, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.
      Catalogue Number204870
      Brand Family Calbiochem®
      References
      ReferencesLuxembourg, A.T. and Cooper, N.R. 1994. J. Immunol. 153, 4448.
      Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA 82, 4235.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥85% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      ContaminantsIgG, IgM, IgA, C5, Factor H, Factor I: ≤trace amounts
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      204870-100UGCN 04055977219661

      Documentation

      Complement C3d, Human Certificates of Analysis

      TitleLot Number
      204870

      References

      Reference overview
      Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol. 153, 4448.
      Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA 82, 4235.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-May-2008 RFH
      DescriptionNative, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30,000. The binding of C3d to CR2 (CD21) receptors present on B-lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Concentration Label Please refer to vial label for lot-specific concentration
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥85% by SDS-PAGE
      ContaminantsIgG, IgM, IgA, C5, Factor H, Factor I: ≤trace amounts
      PreservativeNone
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesLuxembourg, A.T. and Cooper, N.R. 1994. J. Immunol. 153, 4448.
      Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA 82, 4235.