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220411 Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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220411
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
2646-38-0C₂₄H₃₉O₄ · Na

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220411-5GMCN
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      Description
      OverviewBile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.
      Catalogue Number220411
      Brand Family Calbiochem®
      References
      ReferencesRolo, A.P., et al. 2001. Biosci. Rep. 21, 73.
      Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
      Roda, A., et al. 1990. J. Lipid Res. 31, 1433.
      Spivak, W., et al. 1988. Biochem. J. 252, 275.
      Hisadome, T., et al. 1980. Gastroenterol. Jpn. 15, 257.
      Product Information
      CAS number2646-38-0
      FormWhite solid
      Hill FormulaC₂₄H₃₉O₄ · Na
      Chemical formulaC₂₄H₃₉O₄ · Na
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity>95% by TLC
      Physicochemical Information
      Heavy metals<10 ppm
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSFZ2231000
      Safety Information
      R PhraseR: 20/21/22-40

      Harmful by inhalation, in contact with skin and if swallowed.
      Limited evidence of a carcinogenic effect.
      S PhraseS: 22-36-53

      Do not breathe dust.
      Wear suitable protective clothing.
      Avoid exposure - obtain special instructions before use.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage +15°C to +30°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      220411-5GMCN 04055977201093

      Documentation

      Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      220411

      References

      Reference overview
      Rolo, A.P., et al. 2001. Biosci. Rep. 21, 73.
      Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
      Roda, A., et al. 1990. J. Lipid Res. 31, 1433.
      Spivak, W., et al. 1988. Biochem. J. 252, 275.
      Hisadome, T., et al. 1980. Gastroenterol. Jpn. 15, 257.

      Brochure

      Title
      Biological Detergents Brochure
      Bulk Product Guide
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2008 RFH
      DescriptionBile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets.
      FormWhite solid
      CAS number2646-38-0
      RTECSFZ2231000
      Chemical formulaC₂₄H₃₉O₄ · Na
      Structure formulaStructure formula
      Purity>95% by TLC
      SolubilityAqueous buffers or H₂O (20 mg/ml)
      Storage +15°C to +30°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Toxicity Harmful & Carcinogenic / Teratogenic
      Merck USA index14, 2054
      ReferencesRolo, A.P., et al. 2001. Biosci. Rep. 21, 73.
      Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
      Roda, A., et al. 1990. J. Lipid Res. 31, 1433.
      Spivak, W., et al. 1988. Biochem. J. 252, 275.
      Hisadome, T., et al. 1980. Gastroenterol. Jpn. 15, 257.