205531 Sigma-AldrichCA-074 Me - Calbiochem
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
More>> CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B. Less<<CA-074 Me - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester
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Overview
Key Spec Table
| Empirical Formula |
|---|
| C₁₉H₃₁N₃O₆ |
Pricing & Availability
| Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
|---|---|---|---|---|---|---|
| 205531-1MGCN |
|
Plastic ampoule | 1 mg |
|
— |
| Description | |
|---|---|
| Overview | A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B. Reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro. |
| Catalogue Number | 205531 |
| Brand Family | Calbiochem® |
| Synonyms | Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₁₉H₃₁N₃O₆ |
| Chemical formula | C₁₉H₃₁N₃O₆ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | cathepsin B |
| Primary Target IC<sub>50</sub> | 2.24 nM against cathepsin B |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 205531-1MGCN | 07790788048433 |