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05-23-0300 Atrial Natriuretic Factor 1-28, Human - CAS 91917-63-4 - Calbiochem

Atrial Natriuretic Factor 1-28, CAS 91917-63-4, increases the rate of renal excretion. Higher levels are reported in congestive heart failure. Involved in diuresis and blood pressure regulation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: hANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY

Primary Target: Increases the rate of renal excretion
05-23-0300
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
91917-63-4C₁₂₇H₂₀₃N₄₅O₃₉S₃

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      05-23-0300-1MGCN
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          Description
          OverviewIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the natriuretic peptide clearance receptor.
          Catalogue Number05-23-0300
          Brand Family Calbiochem®
          SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
          References
          ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
          Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
          Product Information
          CAS number91917-63-4
          ATP CompetitiveN
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
          Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
          Hygroscopic Hygroscopic
          ReversibleN
          Sold on the basis of peptide contentY
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetIncreases the rate of renal excretion
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          05-23-0300-0.5MGCN 04055977206944
          05-23-0300-1MGCN 04055977206951

          Documentation

          Atrial Natriuretic Factor 1-28, Human - CAS 91917-63-4 - Calbiochem Certificates of Analysis

          TitleLot Number
          05-23-0300

          References

          Reference overview
          Prins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
          Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision18-September-2008 RFH
          SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
          DescriptionIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the clearance receptor.
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          CAS number91917-63-4
          Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
          Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
          Purity≥97% by HPLC
          Solubility5% acetic acid (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          Merck USA index14 1360
          ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
          Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.