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MAB345A4 Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate

Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate detects level of O4 & has been published & validated for use in ICC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases
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MAB345A4
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, M, H, Ch, BICCMAlexaFluor®488Monoclonal Antibody
      Description
      Catalogue NumberMAB345A4
      DescriptionAnti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate
      Background InformationOligodendrocytes and astrocytes are derived from common precursor cells, glioblasts (Sommer, 1981). O-Antigens are sulfatides, which function as differentiation markers on the surface of oligodendrocytes of the central nervous system. O4 is formed postnatally (Schachner, 1981) and is a marker for cell bodies and processes of oligodendrocytes types I and II (hairy eyeball type). During oligodendrocyte differentiation, O4 occurs in pro-oligodendrocytes, but not in O-2A-progenitor cells. O4 occurs from day 3 onwards in cell cultures of embryonic mouse brain. Anti-O4 can be used in myelination, demyelination and remyelination studies and in regeneration experiments.
      References
      Product Information
      FormatAlexaFluor®488
      Control
      • Undifferentiated rat oligodendrocyte precursor cells
      PresentationPurified mouse monoclonal IgM conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      Quality LevelMQ100
      Applications
      ApplicationAnti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate detects level of O4 & has been published & validated for use in ICC.
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenHomogenate of white matter of corpus callosum from bovine brain.
      Clone81 (aka mAB 04)
      HostMouse
      SpecificityThis antibody recognizes Oligodendrocyte marker O4. Also reacts with certain galactolipids in sperm.
      IsotypeIgM
      Species Reactivity
      • Rat
      • Mouse
      • Human
      • Chicken
      • Bovine
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Mouse, Human, Chicken, and Bovine based on 100% sequence homology.
      Antibody TypeMonoclonal Antibody
      Purification MethodPrecipitation followed by ion exchange purification
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in undifferentiated rat oligodendrocyte precursor cells.

      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected O4 in undifferentiated rat oligodendrocyte precursor cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB345A4 04053252688881

      Documentation

      Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate Certificates of Analysis

      TitleLot Number
      Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - 2141745 2141745
      Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - 2031357 2031357
      Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - 2234226 2234226
      Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - Q1988591 Q1988591
      Anti-O4, clone 81, Alexa Fluor®488 Conjugate 2970675
      Anti-O4, clone 81, Alexa Fluor®488 Conjugate - 2383606 2383606
      Anti-O4, clone 81, Alexa Fluor®488 Conjugate - 2318827 2318827
      Anti-O4, clone 81, Alexa Fluor®488 Conjugate - 2887525 2887525
      Anti-O4, clone 81, Alexa Fluor®488 Conjugate -2515522 2515522
      Anti-O4, clone 81, Alexa Fluor®488 Conjugate -2581364 2581364
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